Acute D3 Antagonist GSK598809 Selectively Enhances Neural Response during Monetary Reward Anticipation in Drug and Alcohol Dependence

• Main Authors: Murphy, A, Nestor, L.J, McGonigle, J, Paterson, L, Boyapati, V, Ersche, K.D, Flechais, R, Kuchibatla, S, Metastasio, A, Orban, C, Passetti, F, Reed, L, Smith, D, Suckling, J, Taylor, E, Robbins, T.W, Lingford-Hughes, A, Nutt, D.J, Deakin, J.F.W, Elliott, R
• Other Authors: DEPT OF ELECTRICAL & COMPUTER ENGG
• Format: Article
• Published: Nature Publishing Group 2020
• Subjects: alcohol; gsk 598809; placebo; azabicyclo derivative; dopamine 3 receptor; oxazole derivative; alcoholism; anticipation; Article; BOLD signal; clinical article; controlled study; crossover procedure; double blind procedure; drug dependence; frontal cortex; functional magnetic resonance imaging; functional neuroimaging; human; inhibition (psychology); multicenter study; priority journal; reward; substantia nigra; ventral pallidum; adult; antagonists and inhibitors; brain; brain mapping; drug effects; female; male; middle aged; nuclear magnetic resonance imaging; pathophysiology; psychology; young adult; Adult; Alcoholism; Anticipation, Psychological; Azabicyclo Compounds; Brain; Brain Mapping; Double-Blind Method; Female; Humans; Inhibition (Psychology); Magnetic Resonance Imaging; Male; Middle Aged; Oxazoles; Receptors, Dopamine D3; Reward; Substance-Related Disorders; Young Adult
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/179215
• Institution: National University of Singapore

10.1038/npp.2016.289