MIR-524-5p of the primate-specific C19MC miRNA cluster targets TP53IPN1-and EMT-Associated genes to regulate cellular reprogramming

• Main Authors: Nguyen, P.N.N, Choo, K.B, Huang, C.-J, Sugii, S, Cheong, S.K, Kamarul, T
• Other Authors: DUKE-NUS MEDICAL SCHOOL
• Format: Article
• Published: 2020
• Subjects: chromosome 19 miRNA; kruppel like factor 4; messenger RNA; microRNA; microRNA 524 5p; Myc protein; octamer transcription factor 4; reactive oxygen metabolite; Rex protein; Rex1 protein; Smad3 protein; Smad4 protein; TP53INP 1 protein; transcription factor; transcription factor NANOG; transcription factor Sox2; transcription factor ZEB1; transcription factor ZEB2; Twist related protein 1; unclassified drug; carrier protein; heat shock protein; MIRN-524 microRNA, human; SMAD4 protein, human; TP53INP1 protein, human; ZEB2 protein, human; zinc finger E box binding homeobox 2; 3' untranslated region; amino acid sequence; animal cell; apoptosis; Article; bioinformatics; cell death; cell differentiation; cell viability; chromosome 19; cluster analysis; controlled study; down regulation; enzyme linked immunosorbent assay; epithelial mesenchymal transition; fibroblast; gene targeting; human; human cell; mesenchymal stem cell; microarray analysis; nonhuman; nuclear reprogramming; phylogenetic tree; primate; priority journal; protein expression; protein function; protein targeting; real time polymerase chain reaction; sequence alignment; upregulation; Western blotting; genetics; metabolism; tumor cell line; Carrier Proteins; Cell Line, Tumor; Cellular Reprogramming; Epithelial-Mesenchymal Transition; Heat-Shock Proteins; Humans; MicroRNAs; Smad4 Protein; Zinc Finger E-box Binding Homeobox 2
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/179457
• Institution: National University of Singapore

10.1186/s13287-017-0666-3