Family history of early infant death correlates with earlier age at diagnosis but not shorter time to diagnosis for severe combined immunodeficiency

• Main Authors: Wai Luk, A.D, Lee, P.P, Mao, H
• Other Authors: PAEDIATRICS
• Format: Article
• Published: 2020
• Subjects: adenosine deaminase; CD19 antigen; CD3 antigen; Janus kinase 3; RAG1 protein; RAG2 protein; adolescent; adult; age; Article; autosomal recessive severe combined immunodeficiency; B lymphocyte; bovine tuberculosis; candidiasis; child; child death; clinical feature; early diagnosis; failure to thrive; family history; female; gene mutation; genetic analysis; genotype; human; infant; lymphocyte count; major clinical study; male; Mycobacterium bovis BCG; onset age; opportunistic infection; recurrent infection; severe combined immunodeficiency; time to treatment; X linked severe combined immunodeficiency
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/179475
• Institution: National University of Singapore

10.3389/fimmu.2017.00808