RIG-I antiviral signaling drives interleukin-23 production and psoriasis-like skin disease

• Main Authors: Zhu, H, Lou, F, Yin, Q, Gao, Y, Sun, Y, Bai, J, Xu, Z, Liu, Z, Cai, W, Ke, F, Zhang, L, Zhou, H, Wang, H, Wang, G, Chen, X, Zhang, H, Wang, Z, Ginhoux, F, Lu, C, Su, B
• Other Authors: MICROBIOLOGY AND IMMUNOLOGY
• Format: Article
• Published: 2020
• Subjects: double stranded RNA; glycoprotein p 15095; immunoglobulin enhancer binding protein; interleukin 23; messenger RNA; pattern recognition receptor; retinoic acid inducible protein I; DDX58 protein, human; Ddx58 protein, mouse; animal experiment; animal model; Article; controlled study; cytokine production; dendritic cell; dermatitis; gene expression; hematopoietic cell; host; human; human tissue; immune response; inflammatory cell; innate immunity; keratinocyte; mouse; nonhuman; pathophysiology; phenotype; protein expression; psoriasis; signal transduction; adolescent; adult; animal; C57BL mouse; child; female; immunology; male; middle aged; pathology; preschool child; RNA virus; RNA virus infection; skin; skin disease; young adult; Adolescent; Adult; Animals; Child; Child, Preschool; DEAD Box Protein 58; Dendritic Cells; Female; Humans; Interleukin-23; Male; Mice; Mice, Inbred C57BL; Middle Aged; NF-kappa B; Psoriasis; RNA Virus Infections; RNA Viruses; Signal Transduction; Skin; Skin Diseases; Young Adult
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/179508
• Institution: National University of Singapore

10.15252/emmm.201607027