Reducing myocardial infarct size: Challenges and future opportunities

• Main Authors: Bulluck, H, Yellon, D.M, Hausenloy, D.J
• Other Authors: DUKE-NUS MEDICAL SCHOOL
• Format: Review
• Published: BMJ Publishing Group 2020
• Subjects: adenosine; antiinflammatory agent; antioxidant; atorvastatin; atrial natriuretic factor; atrial natriuretic factor alpha; calcium channel blocking agent; cyclosporin A; delcasertib; elamipretide; erythropoietin; exendin 4; glucose; insulin; magnesium; metoprolol; nitric oxide; placebo; potassium; protein inhibitor; sodium nitrite; tro 40303; unclassified drug; cardiovascular agent; acute heart infarction; death; drug effect; drug efficacy; drug mechanism; drug targeting; heart failure; heart infarction; heart infarction size; heart muscle reperfusion; heart protection; human; induced hypothermia; ischemic postconditioning; limb ischemia; nonhuman; patient selection; percutaneous coronary intervention; percutaneous transluminal angioplasty; priority journal; reperfusion injury; Review; single drug dose; ST segment elevation myocardial infarction; therapy effect; adverse effects; animal; cardiac muscle; ischemic preconditioning; metabolism; mortality; Myocardial Infarction; Myocardial Reperfusion Injury; pathology; pathophysiology; procedures; risk factor; treatment outcome; Animals; Cardiovascular Agents; Heart Failure; Humans; Ischemic Postconditioning; Ischemic Preconditioning; Myocardium; Percutaneous Coronary Intervention; Risk Factors; Treatment Outcome
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/179591
• Institution: National University of Singapore

10.1136/heartjnl-2015-307855