ISL1 is a major susceptibility gene for classic bladder exstrophy and a regulator of urinary tract development

• Main Authors: Zhang, R, Knapp, M, Suzuki, K
• Other Authors: MICROBIOLOGY AND IMMUNOLOGY
• Format: Article
• Published: Nature Publishing Group 2020
• Subjects: insulin gene enhancer binding protein Isl-1; isoprotein; LIM homeodomain protein; transcription factor; abnormalities; animal; bladder exstrophy; female; gene expression regulation; genetic predisposition; genetics; growth, development and aging; human; larva; mammalian embryo; mesoderm; metabolism; mouse; organogenesis; pathology; pronephros; single nucleotide polymorphism; urinary tract; zebra fish; Animals; Bladder Exstrophy; Embryo, Mammalian; Female; Gene Expression Regulation, Developmental; Genetic Predisposition to Disease; Humans; Larva; LIM-Homeodomain Proteins; Mesoderm; Mice; Organogenesis; Polymorphism, Single Nucleotide; Pronephros; Protein Isoforms; Transcription Factors; Urinary Tract; Zebrafish
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/179736
• Institution: National University of Singapore

10.1038/srep42170