Three-dimensional aligned nanofibers-hydrogel scaffold for controlled non-viral drug/gene delivery to direct axon regeneration in spinal cord injury treatment

• Main Authors: Nguyen, L.H, Gao, M, Lin, J, Wu, W, Wang, J, Chew, S.Y
• Other Authors: DEPT OF BIOCHEMISTRY
• Format: Article
• Published: Nature Publishing Group 2020
• Subjects: nanofiber; animal; axon; chemistry; drug delivery system; female; gene transfer; hydrogel; intermediate filament; metabolism; nerve regeneration; pathology; pathophysiology; remyelinization; spinal cord; spinal cord injury; Sprague Dawley rat; three dimensional imaging; tissue scaffold; Animals; Axons; Drug Delivery Systems; Female; Gene Transfer Techniques; Hydrogels; Imaging, Three-Dimensional; Intermediate Filaments; Nanofibers; Nerve Regeneration; Rats, Sprague-Dawley; Remyelination; Spinal Cord; Spinal Cord Injuries; Tissue Scaffolds
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/179737
• Institution: National University of Singapore

10.1038/srep42212