Crystal structure of a PP2A B56-BubR1 complex and its implications for PP2A substrate recruitment and localization

• Main Authors: Wang, J, Wang, Z, Yu, T, Yang, H, Virshup, D.M, Kops, G.J.P.L, Lee, S.H, Zhou, W, Li, X, Xu, W, Rao, Z
• Other Authors: DUKE-NUS MEDICAL SCHOOL
• Format: Article
• Published: 2020
• Subjects: binding protein; Bub1 related protein; phosphopeptide; phosphoprotein phosphatase 2A; BUB1 protein, human; cell cycle protein; multienzyme complex; phosphoprotein phosphatase 2; PP2A-B56alpha protein, human; protein serine threonine kinase; SGOL1 protein, human; Article; cell division; chemical mutagenesis; chromosome segregation; crystal structure; DNA binding motif; enzyme specificity; gene expression regulation; human; isothermal titration calorimetry; kinetochore microtubule; M phase cell cycle checkpoint; polyacrylamide gel electrophoresis; priority journal; protein expression; protein interaction; protein localization; protein phosphorylation; protein processing; protein purification; proteomics; transcription regulation; binding site; chemistry; protein motif; protein quaternary structure; X ray crystallography; Amino Acid Motifs; Binding Sites; Cell Cycle Proteins; Crystallography, X-Ray; Humans; Multienzyme Complexes; Protein Phosphatase 2; Protein Structure, Quaternary; Protein-Serine-Threonine Kinases
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/179923
• Institution: National University of Singapore

10.1007/s13238-016-0283-4