Short chain acyl-CoA dehydrogenase deficiency and short-term high-fat diet perturb mitochondrial energy metabolism and transcriptional control of lipid-handling in liver

• Main Authors: Ghosh, S, Kruger, C, Wicks, S, Simon, J, Kumar, K.G, Johnson, W.D, Mynatt, R.L, Noland, R.C, Richards, B.K
• Other Authors: DUKE-NUS MEDICAL SCHOOL
• Format: Article
• Published: 2020
• Subjects: acylcarnitine; hydroxymethylglutaryl coenzyme A reductase kinase; mitochondrial DNA; peroxisome proliferator activated receptor alpha; retinoid X receptor; animal cell; animal experiment; animal model; animal tissue; Article; cell proliferation; controlled study; electron transport; energy balance; energy metabolism; enzyme activation; enzyme phosphorylation; fatty acid oxidation; gene; gene expression; lipid diet; male; mitochondrial respiration; mouse; multiple acyl CoA dehydrogenase deficiency; Nfe2l2 gene; nonhuman; oxidative phosphorylation; oxygen consumption; signal transduction; transcription regulation; upregulation
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/179938
• Institution: National University of Singapore

10.1186/s12986-016-0075-0