Germline and somatic SDHx alterations in apparently sporadic differentiated thyroid cancer

• Main Authors: Ni, Y, Seballos, S, Ganapathi, S, Gurin, D, Fletcher, B, Ngeow, J, Nagy, R, Kloos, R.T, Ringel, M.D, LaFramboise, T, Eng, C
• Other Authors: DUKE-NUS MEDICAL SCHOOL
• Format: Article
• Published: BioScientifica Ltd. 2020
• Subjects: protein; SDHx protein; unclassified drug; membrane protein; SDHB protein, human; SDHC protein, human; SDHD protein, human; succinate dehydrogenase; adult; aged; Article; breast adenocarcinoma; cancer staging; carcinogenesis; chromosome 1; chromosome duplication; comparative study; controlled study; copy number variation; differentiated thyroid cancer; female; gene; gene expression; gene loss; genetic association; genetic variability; germline mutation; human; invasive carcinoma; major clinical study; male; middle aged; sdhx gene; somatic mutation; thyroid carcinoma; thyroid follicular carcinoma; adenocarcinoma; breast tumor; carcinoma; genetics; mutation; Paget nipple disease; thyroid tumor; very elderly; Adenocarcinoma, Follicular; Adult; Aged; Aged, 80 and over; Breast Neoplasms; Carcinoma; Carcinoma, Ductal, Breast; Female; Genetic Variation; Humans; Membrane Proteins; Middle Aged; Mutation; Succinate Dehydrogenase; Thyroid Neoplasms
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/180118
• Institution: National University of Singapore

10.1530/ERC-14-0537