Effectiveness of antimicrobial peptide immobilization for preventing perioperative cornea implant-associated bacterial infection

• Main Authors: Tan, X.W, Goh, T.W, Saraswathi, P, Nyein, C.L, Setiawan, M, Riau, A, Lakshminarayanan, R, Liu, S, Tan, D, Beuerman, R.W, Mehta, J.S
• Other Authors: DUKE-NUS MEDICAL SCHOOL
• Format: Article
• Published: American Society for Microbiology 2020
• Subjects: polypeptide antibiotic agent; prednisolone acetate; antiinfective agent; antimicrobial cationic peptide; titanium; animal experiment; animal model; antibiotic therapy; article; bacterial viability; bactericidal activity; controlled study; cornea disease; cornea implant associated bacterial infection; cornea thickness; drug efficacy; eye inflammation; femtosecond laser; fluorescence microscopy; graft infection; immunofluorescence test; in vitro study; in vivo study; inflammation; keratitis; minimum inhibitory concentration; nonhuman; optical coherence tomography; priority journal; Pseudomonas aeruginosa; rabbit; slit lamp; Staphylococcus aureus; adverse effects; animal; cornea transplantation; diagnostic use; Pseudomonas Infections; Staphylococcal Infections; Surgical Wound Infection; Animals; Anti-Bacterial Agents; Antimicrobial Cationic Peptides; Corneal Transplantation; Rabbits; Slit Lamp; Titanium; Tomography, Optical Coherence
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/180170
• Institution: National University of Singapore

10.1128/AAC.02859-14