Distinct regions of NLRP1B are required to respond to anthrax lethal toxin and metabolic inhibition

• Main Authors: Neiman-Zenevich, J, Liao, K.-C, Mogridge, J
• Other Authors: DUKE-NUS MEDICAL SCHOOL
• Format: Article
• Published: American Society for Microbiology 2020
• Subjects: adenosine triphosphate; anthrax toxin; cell receptor; glucose; interleukin 1beta; leucine; pattern recognition receptor; protein NLRP1B; unclassified drug; allele; amino acid sequence; amino terminal sequence; article; ATPase activity assay; cell death; controlled study; cytokine production; cytokine release; cytosol; deletion mutant; exon; gene duplication; human; human cell; immune response; lethal gene; lethality; metabolic inhibition; priority journal; protein domain; protein function; protein protein interaction; respiratory chain; signal transduction; site directed mutagenesis; Adenosine Triphosphate; Anthrax; Antigens, Bacterial; Apoptosis Regulatory Proteins; Bacillus anthracis; Bacterial Toxins; Cell Line; Humans; Inflammasomes; Leucine; Receptors, Pattern Recognition
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/180172
• Institution: National University of Singapore

10.1128/IAI.02167-14