Progerin reduces LAP2?-telomere association in hutchinson-gilford progeria

• Main Authors: Chojnowski, A, Ong, P.F, Wong, E.S.M, Lim, J.S.Y, Mutalif, R.A, Navasankari, R, Dutta, B, Yang, H, Liow, Y.Y, Sze, S.K, Boudier, T, Wright, G.D, Colman, A, Burke, B, Stewart, C.L, Dreesen, O
• Other Authors: CANCER SCIENCE INSTITUTE OF SINGAPORE
• Format: Article
• Published: 2020
• Subjects: doxycycline; lamin A; lamin B; lamina associated polypeptide alpha; progerin; telomerase; unclassified drug; DNA binding protein; lamina-associated polypeptide 2; membrane protein; prelamin A; protein binding; animal cell; Article; biotinylation; cell differentiation; cell proliferation; chromatin; controlled study; DNA damage; gene mutation; heterochromatin; Hutchinson Gilford progeria; image analysis; immunoblotting; immunofluorescence; immunofluorescence microscopy; immunoprecipitation; mouse; nonhuman; progeria; protein expression; protein interaction; protein localization; protein microarray; senescence; human; metabolism; microscopy; pathology; telomere; DNA-Binding Proteins; Humans; Lamin Type A; Membrane Proteins; Microscopy; Progeria; Protein Binding; Telomere
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/180322
• Institution: National University of Singapore

10.7554/eLife.07759