Musashi proteins are post-transcriptional regulators of the epithelial-luminal cell state

• Main Authors: Katz, Y, Li, F, Lambert, N.J, Sokol, E.S, Tam, W.-L, Cheng, A.W, Airoldi, E.M, Lengner, C.J, Gupta, P.B, Yu, Z, Jaenisch, R, Burge, C.B
• Other Authors: DEPT OF BIOCHEMISTRY
• Format: Article
• Published: 2020
• Subjects: Jagged1; Musashi protein; RNA binding protein; unclassified drug; calcium binding protein; ligand; membrane protein; nerve protein; Notch receptor; protein binding; Serrate proteins; signal peptide; Article; cancer cell; cell differentiation; controlled study; down regulation; epithelial mesenchymal transition; gene mutation; gene overexpression; genetic variability; human; human cell; human tissue; protein depletion; protein expression; RNA processing; RNA splicing; upregulation; alternative RNA splicing; animal; biological model; breast; breast tumor; epithelium cell; female; gene expression regulation; genetic transcription; genetics; growth, development and aging; knockout mouse; metabolism; molecular genetics; morphogenesis; neural stem cell; nucleotide motif; nucleotide sequence; pathology; protein synthesis; tumor cell line; Mammalia; Alternative Splicing; Animals; Base Sequence; Breast; Breast Neoplasms; Calcium-Binding Proteins; Cell Line, Tumor; Down-Regulation; Epithelial Cells; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; Humans; Intercellular Signaling Peptides and Proteins; Ligands; Membrane Proteins; Mice, Knockout; Models, Biological; Molecular Sequence Data; Morphogenesis; Nerve Tissue Proteins; Neural Stem Cells; Nucleotide Motifs; Protein Binding; Protein Biosynthesis; Receptors, Notch; RNA-Binding Proteins; Transcription, Genetic
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/180375
• Institution: National University of Singapore

10.7554/eLife.03915