Kindlin-3 interacts with the ribosome and regulates c-Myc expression required for proliferation of chronic myeloid leukemia cells

10.1038/srep18491

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Main Authors: Qu, J, Ero, R, Feng, C, Ong, L.-T, Tan, H.-F, Lee, H.-S, Ismail, M.H, Bu, W.-T, Nama, S, Sampath, P, Gao, Y.-G, Tan, S.-M
Other Authors: BIOCHEMISTRY
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Published: Nature Publishing Group 2020
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Online Access:https://scholarbank.nus.edu.sg/handle/10635/180401
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spelling sg-nus-scholar.10635-1804012024-11-08T16:58:30Z Kindlin-3 interacts with the ribosome and regulates c-Myc expression required for proliferation of chronic myeloid leukemia cells Qu, J Ero, R Feng, C Ong, L.-T Tan, H.-F Lee, H.-S Ismail, M.H Bu, W.-T Nama, S Sampath, P Gao, Y.-G Tan, S.-M BIOCHEMISTRY antineoplastic antibiotic beta3 integrin cell surface receptor GNB2L1 protein, human guanine nucleotide binding protein membrane protein MIG2B protein, human Myc protein protein binding rapamycin recombinant protein target of rapamycin kinase tumor protein animal antagonists and inhibitors Bagg albino mouse biosynthesis cell proliferation chemistry chronic myeloid leukemia drug effects genetics HEK293 cell line human isolation and purification K-562 cell line knockout mouse metabolism mouse pathology ribosome RNA interference signal transduction umbilical vein endothelial cell Animals Antibiotics, Antineoplastic Cell Proliferation GTP-Binding Proteins HEK293 Cells Human Umbilical Vein Endothelial Cells Humans Integrin beta3 K562 Cells Leukemia, Myelogenous, Chronic, BCR-ABL Positive Membrane Proteins Mice Mice, Inbred BALB C Mice, Knockout Neoplasm Proteins Protein Binding Proto-Oncogene Proteins c-myc Receptors, Cell Surface Recombinant Proteins Ribosomes RNA Interference Signal Transduction Sirolimus TOR Serine-Threonine Kinases 10.1038/srep18491 Scientific Reports 5 18491 2020-10-26T08:49:08Z 2020-10-26T08:49:08Z 2015 Article Qu, J, Ero, R, Feng, C, Ong, L.-T, Tan, H.-F, Lee, H.-S, Ismail, M.H, Bu, W.-T, Nama, S, Sampath, P, Gao, Y.-G, Tan, S.-M (2015). Kindlin-3 interacts with the ribosome and regulates c-Myc expression required for proliferation of chronic myeloid leukemia cells. Scientific Reports 5 : 18491. ScholarBank@NUS Repository. https://doi.org/10.1038/srep18491 2045-2322 https://scholarbank.nus.edu.sg/handle/10635/180401 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Nature Publishing Group Unpaywall 20201031
institution National University of Singapore
building NUS Library
continent Asia
country Singapore
Singapore
content_provider NUS Library
collection ScholarBank@NUS
topic antineoplastic antibiotic
beta3 integrin
cell surface receptor
GNB2L1 protein, human
guanine nucleotide binding protein
membrane protein
MIG2B protein, human
Myc protein
protein binding
rapamycin
recombinant protein
target of rapamycin kinase
tumor protein
animal
antagonists and inhibitors
Bagg albino mouse
biosynthesis
cell proliferation
chemistry
chronic myeloid leukemia
drug effects
genetics
HEK293 cell line
human
isolation and purification
K-562 cell line
knockout mouse
metabolism
mouse
pathology
ribosome
RNA interference
signal transduction
umbilical vein endothelial cell
Animals
Antibiotics, Antineoplastic
Cell Proliferation
GTP-Binding Proteins
HEK293 Cells
Human Umbilical Vein Endothelial Cells
Humans
Integrin beta3
K562 Cells
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Membrane Proteins
Mice
Mice, Inbred BALB C
Mice, Knockout
Neoplasm Proteins
Protein Binding
Proto-Oncogene Proteins c-myc
Receptors, Cell Surface
Recombinant Proteins
Ribosomes
RNA Interference
Signal Transduction
Sirolimus
TOR Serine-Threonine Kinases
spellingShingle antineoplastic antibiotic
beta3 integrin
cell surface receptor
GNB2L1 protein, human
guanine nucleotide binding protein
membrane protein
MIG2B protein, human
Myc protein
protein binding
rapamycin
recombinant protein
target of rapamycin kinase
tumor protein
animal
antagonists and inhibitors
Bagg albino mouse
biosynthesis
cell proliferation
chemistry
chronic myeloid leukemia
drug effects
genetics
HEK293 cell line
human
isolation and purification
K-562 cell line
knockout mouse
metabolism
mouse
pathology
ribosome
RNA interference
signal transduction
umbilical vein endothelial cell
Animals
Antibiotics, Antineoplastic
Cell Proliferation
GTP-Binding Proteins
HEK293 Cells
Human Umbilical Vein Endothelial Cells
Humans
Integrin beta3
K562 Cells
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Membrane Proteins
Mice
Mice, Inbred BALB C
Mice, Knockout
Neoplasm Proteins
Protein Binding
Proto-Oncogene Proteins c-myc
Receptors, Cell Surface
Recombinant Proteins
Ribosomes
RNA Interference
Signal Transduction
Sirolimus
TOR Serine-Threonine Kinases
Qu, J
Ero, R
Feng, C
Ong, L.-T
Tan, H.-F
Lee, H.-S
Ismail, M.H
Bu, W.-T
Nama, S
Sampath, P
Gao, Y.-G
Tan, S.-M
Kindlin-3 interacts with the ribosome and regulates c-Myc expression required for proliferation of chronic myeloid leukemia cells
description 10.1038/srep18491
author2 BIOCHEMISTRY
author_facet BIOCHEMISTRY
Qu, J
Ero, R
Feng, C
Ong, L.-T
Tan, H.-F
Lee, H.-S
Ismail, M.H
Bu, W.-T
Nama, S
Sampath, P
Gao, Y.-G
Tan, S.-M
format Article
author Qu, J
Ero, R
Feng, C
Ong, L.-T
Tan, H.-F
Lee, H.-S
Ismail, M.H
Bu, W.-T
Nama, S
Sampath, P
Gao, Y.-G
Tan, S.-M
author_sort Qu, J
title Kindlin-3 interacts with the ribosome and regulates c-Myc expression required for proliferation of chronic myeloid leukemia cells
title_short Kindlin-3 interacts with the ribosome and regulates c-Myc expression required for proliferation of chronic myeloid leukemia cells
title_full Kindlin-3 interacts with the ribosome and regulates c-Myc expression required for proliferation of chronic myeloid leukemia cells
title_fullStr Kindlin-3 interacts with the ribosome and regulates c-Myc expression required for proliferation of chronic myeloid leukemia cells
title_full_unstemmed Kindlin-3 interacts with the ribosome and regulates c-Myc expression required for proliferation of chronic myeloid leukemia cells
title_sort kindlin-3 interacts with the ribosome and regulates c-myc expression required for proliferation of chronic myeloid leukemia cells
publisher Nature Publishing Group
publishDate 2020
url https://scholarbank.nus.edu.sg/handle/10635/180401
_version_ 1821205879786045440