Novel RNA-and FMRP-binding protein TRF2-S regulates axonal mRNA transport and presynaptic plasticity

• Main Authors: Zhang, P, Abdelmohsen, K, Liu, Y, Tominaga-Yamanaka, K, Yoon, J.-H, Ioannis, G, Martindale, J.L, Zhang, Y, Becker, K.G, Yang, I.H, Gorospe, M, Mattson, M.P
• Other Authors: LIFE SCIENCES INSTITUTE
• Format: Article
• Published: Nature Publishing Group 2020
• Subjects: alpha tubulin; fragile X mental retardation protein; messenger RNA; telomeric repeat binding factor 2; TRF2 S protein; unclassified drug; carrier protein; Fmr1 protein, mouse; RNA binding protein; TRF2 protein, mouse; genetic analysis; neurology; plasticity; protein; RNA; adult; animal experiment; animal tissue; Article; binding site; brain cell; cell differentiation; cell growth; controlled study; dendrite; Enterobacteria phage MS2; female; hippocampal neuronal culture; human; human cell; mitochondrial membrane; mouse; multigene family; nerve cell plasticity; nerve fiber; neurotransmitter release; nonhuman; nuclear export signal; presynaptic nerve; protein assembly; protein cross linking; protein domain; protein expression; protein motif; protein RNA binding; rat; reverse transcription; RNA transport; synaptic transmission; synaptogenesis; synaptosome; animal; axon; C57BL mouse; genetics; knockout mouse; male; metabolism; nerve fiber transport; Sprague Dawley rat; transport at the cellular level; Animals; Axonal Transport; Axons; Biological Transport; Carrier Proteins; Female; Fragile X Mental Retardation Protein; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Rats; Rats, Sprague-Dawley; RNA, Messenger; RNA-Binding Proteins; Telomeric Repeat Binding Protein 2
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/180414
• Institution: National University of Singapore

10.1038/ncomms9888