Chip-based analysis of exosomal mRNA mediating drug resistance in glioblastoma

10.1038/ncomms7999

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Main Authors:	Shao, H, Chung, J, Lee, K, Balaj, L, Min, C, Carter, B.S, Hochberg, F.H, Breakefield, X.O, Lee, H, Weissleder, R
Other Authors:	BIOMEDICAL ENGINEERING
Format:	Article
Published:	Nature Publishing Group 2020
Subjects:	messenger RNA methylated DNA protein cysteine methyltransferase dacarbazine temozolomide tumor marker disease treatment drug resistance enzyme activity gene expression methylation RNA tumor Article blood brain barrier cancer resistance cell culture cohort analysis controlled study DNA methylation drug efficacy drug response exosome gene product glioblastoma human human cell microfluidics promoter region radiotherapy reverse transcription RNA analysis RNA extraction therapy treatment outcome treatment response tumor biopsy analogs and derivatives animal Brain Neoplasms drug effects female gene expression profiling gene expression regulation genetics immunomagnetic separation metabolism nude mouse procedures tumor cell line Animals Biomarkers, Tumor Cell Line, Tumor Dacarbazine Drug Resistance, Neoplasm Exosomes Female Gene Expression Profiling Gene Expression Regulation, Neoplastic Glioblastoma Humans Immunomagnetic Separation Mice, Nude Microfluidics RNA, Messenger Treatment Outcome
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/180471
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Institution:	National University of Singapore

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spelling	sg-nus-scholar.10635-1804712023-10-31T21:19:45Z Chip-based analysis of exosomal mRNA mediating drug resistance in glioblastoma Shao, H Chung, J Lee, K Balaj, L Min, C Carter, B.S Hochberg, F.H Breakefield, X.O Lee, H Weissleder, R BIOMEDICAL ENGINEERING messenger RNA methylated DNA protein cysteine methyltransferase dacarbazine messenger RNA temozolomide tumor marker disease treatment drug resistance enzyme activity gene expression methylation RNA tumor Article blood brain barrier cancer resistance cell culture cohort analysis controlled study DNA methylation drug efficacy drug response exosome gene product glioblastoma human human cell methylation microfluidics promoter region radiotherapy reverse transcription RNA analysis RNA extraction therapy treatment outcome treatment response tumor biopsy analogs and derivatives animal Brain Neoplasms drug effects drug resistance female gene expression profiling gene expression regulation genetics glioblastoma immunomagnetic separation metabolism nude mouse procedures tumor cell line Animals Biomarkers, Tumor Brain Neoplasms Cell Line, Tumor Dacarbazine Drug Resistance, Neoplasm Exosomes Female Gene Expression Profiling Gene Expression Regulation, Neoplastic Glioblastoma Humans Immunomagnetic Separation Mice, Nude Microfluidics RNA, Messenger Treatment Outcome 10.1038/ncomms7999 Nature Communications 6 6999 2020-10-26T09:07:45Z 2020-10-26T09:07:45Z 2015 Article Shao, H, Chung, J, Lee, K, Balaj, L, Min, C, Carter, B.S, Hochberg, F.H, Breakefield, X.O, Lee, H, Weissleder, R (2015). Chip-based analysis of exosomal mRNA mediating drug resistance in glioblastoma. Nature Communications 6 : 6999. ScholarBank@NUS Repository. https://doi.org/10.1038/ncomms7999 2041-1723 https://scholarbank.nus.edu.sg/handle/10635/180471 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Nature Publishing Group Unpaywall 20201031
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	messenger RNA methylated DNA protein cysteine methyltransferase dacarbazine messenger RNA temozolomide tumor marker disease treatment drug resistance enzyme activity gene expression methylation RNA tumor Article blood brain barrier cancer resistance cell culture cohort analysis controlled study DNA methylation drug efficacy drug response exosome gene product glioblastoma human human cell methylation microfluidics promoter region radiotherapy reverse transcription RNA analysis RNA extraction therapy treatment outcome treatment response tumor biopsy analogs and derivatives animal Brain Neoplasms drug effects drug resistance female gene expression profiling gene expression regulation genetics glioblastoma immunomagnetic separation metabolism nude mouse procedures tumor cell line Animals Biomarkers, Tumor Brain Neoplasms Cell Line, Tumor Dacarbazine Drug Resistance, Neoplasm Exosomes Female Gene Expression Profiling Gene Expression Regulation, Neoplastic Glioblastoma Humans Immunomagnetic Separation Mice, Nude Microfluidics RNA, Messenger Treatment Outcome
spellingShingle	messenger RNA methylated DNA protein cysteine methyltransferase dacarbazine messenger RNA temozolomide tumor marker disease treatment drug resistance enzyme activity gene expression methylation RNA tumor Article blood brain barrier cancer resistance cell culture cohort analysis controlled study DNA methylation drug efficacy drug response exosome gene product glioblastoma human human cell methylation microfluidics promoter region radiotherapy reverse transcription RNA analysis RNA extraction therapy treatment outcome treatment response tumor biopsy analogs and derivatives animal Brain Neoplasms drug effects drug resistance female gene expression profiling gene expression regulation genetics glioblastoma immunomagnetic separation metabolism nude mouse procedures tumor cell line Animals Biomarkers, Tumor Brain Neoplasms Cell Line, Tumor Dacarbazine Drug Resistance, Neoplasm Exosomes Female Gene Expression Profiling Gene Expression Regulation, Neoplastic Glioblastoma Humans Immunomagnetic Separation Mice, Nude Microfluidics RNA, Messenger Treatment Outcome Shao, H Chung, J Lee, K Balaj, L Min, C Carter, B.S Hochberg, F.H Breakefield, X.O Lee, H Weissleder, R Chip-based analysis of exosomal mRNA mediating drug resistance in glioblastoma
description	10.1038/ncomms7999
author2	BIOMEDICAL ENGINEERING
author_facet	BIOMEDICAL ENGINEERING Shao, H Chung, J Lee, K Balaj, L Min, C Carter, B.S Hochberg, F.H Breakefield, X.O Lee, H Weissleder, R
format	Article
author	Shao, H Chung, J Lee, K Balaj, L Min, C Carter, B.S Hochberg, F.H Breakefield, X.O Lee, H Weissleder, R
author_sort	Shao, H
title	Chip-based analysis of exosomal mRNA mediating drug resistance in glioblastoma
title_short	Chip-based analysis of exosomal mRNA mediating drug resistance in glioblastoma
title_full	Chip-based analysis of exosomal mRNA mediating drug resistance in glioblastoma
title_fullStr	Chip-based analysis of exosomal mRNA mediating drug resistance in glioblastoma
title_full_unstemmed	Chip-based analysis of exosomal mRNA mediating drug resistance in glioblastoma
title_sort	chip-based analysis of exosomal mrna mediating drug resistance in glioblastoma
publisher	Nature Publishing Group
publishDate	2020
url	https://scholarbank.nus.edu.sg/handle/10635/180471
_version_	1781792399077408768

Chip-based analysis of exosomal mRNA mediating drug resistance in glioblastoma

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