Chip-based analysis of exosomal mRNA mediating drug resistance in glioblastoma

10.1038/ncomms7999

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Main Authors: Shao, H, Chung, J, Lee, K, Balaj, L, Min, C, Carter, B.S, Hochberg, F.H, Breakefield, X.O, Lee, H, Weissleder, R
Other Authors: BIOMEDICAL ENGINEERING
Format: Article
Published: Nature Publishing Group 2020
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RNA
Online Access:https://scholarbank.nus.edu.sg/handle/10635/180471
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spelling sg-nus-scholar.10635-1804712023-10-31T21:19:45Z Chip-based analysis of exosomal mRNA mediating drug resistance in glioblastoma Shao, H Chung, J Lee, K Balaj, L Min, C Carter, B.S Hochberg, F.H Breakefield, X.O Lee, H Weissleder, R BIOMEDICAL ENGINEERING messenger RNA methylated DNA protein cysteine methyltransferase dacarbazine messenger RNA temozolomide tumor marker disease treatment drug resistance enzyme activity gene expression methylation RNA tumor Article blood brain barrier cancer resistance cell culture cohort analysis controlled study DNA methylation drug efficacy drug response exosome gene product glioblastoma human human cell methylation microfluidics promoter region radiotherapy reverse transcription RNA analysis RNA extraction therapy treatment outcome treatment response tumor biopsy analogs and derivatives animal Brain Neoplasms drug effects drug resistance female gene expression profiling gene expression regulation genetics glioblastoma immunomagnetic separation metabolism nude mouse procedures tumor cell line Animals Biomarkers, Tumor Brain Neoplasms Cell Line, Tumor Dacarbazine Drug Resistance, Neoplasm Exosomes Female Gene Expression Profiling Gene Expression Regulation, Neoplastic Glioblastoma Humans Immunomagnetic Separation Mice, Nude Microfluidics RNA, Messenger Treatment Outcome 10.1038/ncomms7999 Nature Communications 6 6999 2020-10-26T09:07:45Z 2020-10-26T09:07:45Z 2015 Article Shao, H, Chung, J, Lee, K, Balaj, L, Min, C, Carter, B.S, Hochberg, F.H, Breakefield, X.O, Lee, H, Weissleder, R (2015). Chip-based analysis of exosomal mRNA mediating drug resistance in glioblastoma. Nature Communications 6 : 6999. ScholarBank@NUS Repository. https://doi.org/10.1038/ncomms7999 2041-1723 https://scholarbank.nus.edu.sg/handle/10635/180471 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Nature Publishing Group Unpaywall 20201031
institution National University of Singapore
building NUS Library
continent Asia
country Singapore
Singapore
content_provider NUS Library
collection ScholarBank@NUS
topic messenger RNA
methylated DNA protein cysteine methyltransferase
dacarbazine
messenger RNA
temozolomide
tumor marker
disease treatment
drug resistance
enzyme activity
gene expression
methylation
RNA
tumor
Article
blood brain barrier
cancer resistance
cell culture
cohort analysis
controlled study
DNA methylation
drug efficacy
drug response
exosome
gene product
glioblastoma
human
human cell
methylation
microfluidics
promoter region
radiotherapy
reverse transcription
RNA analysis
RNA extraction
therapy
treatment outcome
treatment response
tumor biopsy
analogs and derivatives
animal
Brain Neoplasms
drug effects
drug resistance
female
gene expression profiling
gene expression regulation
genetics
glioblastoma
immunomagnetic separation
metabolism
nude mouse
procedures
tumor cell line
Animals
Biomarkers, Tumor
Brain Neoplasms
Cell Line, Tumor
Dacarbazine
Drug Resistance, Neoplasm
Exosomes
Female
Gene Expression Profiling
Gene Expression Regulation, Neoplastic
Glioblastoma
Humans
Immunomagnetic Separation
Mice, Nude
Microfluidics
RNA, Messenger
Treatment Outcome
spellingShingle messenger RNA
methylated DNA protein cysteine methyltransferase
dacarbazine
messenger RNA
temozolomide
tumor marker
disease treatment
drug resistance
enzyme activity
gene expression
methylation
RNA
tumor
Article
blood brain barrier
cancer resistance
cell culture
cohort analysis
controlled study
DNA methylation
drug efficacy
drug response
exosome
gene product
glioblastoma
human
human cell
methylation
microfluidics
promoter region
radiotherapy
reverse transcription
RNA analysis
RNA extraction
therapy
treatment outcome
treatment response
tumor biopsy
analogs and derivatives
animal
Brain Neoplasms
drug effects
drug resistance
female
gene expression profiling
gene expression regulation
genetics
glioblastoma
immunomagnetic separation
metabolism
nude mouse
procedures
tumor cell line
Animals
Biomarkers, Tumor
Brain Neoplasms
Cell Line, Tumor
Dacarbazine
Drug Resistance, Neoplasm
Exosomes
Female
Gene Expression Profiling
Gene Expression Regulation, Neoplastic
Glioblastoma
Humans
Immunomagnetic Separation
Mice, Nude
Microfluidics
RNA, Messenger
Treatment Outcome
Shao, H
Chung, J
Lee, K
Balaj, L
Min, C
Carter, B.S
Hochberg, F.H
Breakefield, X.O
Lee, H
Weissleder, R
Chip-based analysis of exosomal mRNA mediating drug resistance in glioblastoma
description 10.1038/ncomms7999
author2 BIOMEDICAL ENGINEERING
author_facet BIOMEDICAL ENGINEERING
Shao, H
Chung, J
Lee, K
Balaj, L
Min, C
Carter, B.S
Hochberg, F.H
Breakefield, X.O
Lee, H
Weissleder, R
format Article
author Shao, H
Chung, J
Lee, K
Balaj, L
Min, C
Carter, B.S
Hochberg, F.H
Breakefield, X.O
Lee, H
Weissleder, R
author_sort Shao, H
title Chip-based analysis of exosomal mRNA mediating drug resistance in glioblastoma
title_short Chip-based analysis of exosomal mRNA mediating drug resistance in glioblastoma
title_full Chip-based analysis of exosomal mRNA mediating drug resistance in glioblastoma
title_fullStr Chip-based analysis of exosomal mRNA mediating drug resistance in glioblastoma
title_full_unstemmed Chip-based analysis of exosomal mRNA mediating drug resistance in glioblastoma
title_sort chip-based analysis of exosomal mrna mediating drug resistance in glioblastoma
publisher Nature Publishing Group
publishDate 2020
url https://scholarbank.nus.edu.sg/handle/10635/180471
_version_ 1781792399077408768