The effect of Aurora kinases on cell proliferation, cell cycle regulation and metastasis in renal cell carcinoma

• Main Authors: Li, Y, Zhou, W, Wei, L, Jin, J, Tang, K, Li, C, Teh, B.T, Chen, X
• Other Authors: DUKE-NUS MEDICAL SCHOOL
• Format: Article
• Published: 2020
• Subjects: aurora A kinase; aurora B kinase; aurora C kinase; cyclin B; cyclin dependent kinase 1; microRNA; protein tyrosine phosphatase; tozasertib; animal model; animal tissue; antineoplastic activity; article; cell proliferation; cell viability; controlled study; down regulation; enzyme activity; enzyme inhibition; female; G2 phase cell cycle checkpoint; in vitro study; in vivo study; kidney carcinoma; metastasis; molecularly targeted therapy; nonhuman; priority journal; protein expression; tumor volume; tumor xenograft; upregulation; Animals; Carcinoma, Renal Cell; Cell Cycle; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Female; Gene Expression Regulation, Neoplastic; Humans; Kidney Neoplasms; Mice; Mice, Nude; Neoplasm Metastasis; Piperazines; Protein-Serine-Threonine Kinases; RNA Interference; Transplantation, Heterologous; Tumor Burden
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/180815
• Institution: National University of Singapore

10.3892/ijo.2012.1633