Mutations in the D1 domain of von Willebrand factor impair their propeptide-dependent multimerization, intracellular trafficking and secretion

10.1186/s13045-015-0166-9

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Main Authors:	Yin, J, Ma, Z, Su, J, Wang, J.-W, Zhao, X, Ling, J, Bai, X, Ouyang, W, Wang, Z, Yu, Z, Ruan, C
Other Authors:	SURGERY
Format:	Article
Published:	2020
Subjects:	dimer oxidoreductase protein variant von Willebrand factor Article cell migration clinical article controlled study dimerization down regulation embryo endoplasmic reticulum enzyme activity female gene mutation genotype HEK293 cell line human human cell intracellular space male mutational analysis partial thromboplastin time protein analysis protein domain protein expression protein function protein multimerization protein secretion prothrombin time thrombin time von Willebrand disease wild type genetic transfection genetics mutation HEK293 Cells Humans Mutation Transfection von Willebrand Factor
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/180908
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Institution:	National University of Singapore

id	sg-nus-scholar.10635-180908
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spelling	sg-nus-scholar.10635-1809082024-04-25T02:08:30Z Mutations in the D1 domain of von Willebrand factor impair their propeptide-dependent multimerization, intracellular trafficking and secretion Yin, J Ma, Z Su, J Wang, J.-W Zhao, X Ling, J Bai, X Ouyang, W Wang, Z Yu, Z Ruan, C SURGERY dimer oxidoreductase protein variant von Willebrand factor von Willebrand factor Article cell migration clinical article controlled study dimerization down regulation embryo endoplasmic reticulum enzyme activity female gene mutation genotype HEK293 cell line human human cell intracellular space male mutational analysis partial thromboplastin time protein analysis protein domain protein expression protein function protein multimerization protein secretion prothrombin time thrombin time von Willebrand disease wild type genetic transfection genetics mutation HEK293 Cells Humans Mutation Transfection von Willebrand Factor 10.1186/s13045-015-0166-9 Journal of Hematology and Oncology 8 1 73 2020-10-27T05:40:01Z 2020-10-27T05:40:01Z 2015 Article Yin, J, Ma, Z, Su, J, Wang, J.-W, Zhao, X, Ling, J, Bai, X, Ouyang, W, Wang, Z, Yu, Z, Ruan, C (2015). Mutations in the D1 domain of von Willebrand factor impair their propeptide-dependent multimerization, intracellular trafficking and secretion. Journal of Hematology and Oncology 8 (1) : 73. ScholarBank@NUS Repository. https://doi.org/10.1186/s13045-015-0166-9 17568722 https://scholarbank.nus.edu.sg/handle/10635/180908 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Unpaywall 20201031
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	dimer oxidoreductase protein variant von Willebrand factor von Willebrand factor Article cell migration clinical article controlled study dimerization down regulation embryo endoplasmic reticulum enzyme activity female gene mutation genotype HEK293 cell line human human cell intracellular space male mutational analysis partial thromboplastin time protein analysis protein domain protein expression protein function protein multimerization protein secretion prothrombin time thrombin time von Willebrand disease wild type genetic transfection genetics mutation HEK293 Cells Humans Mutation Transfection von Willebrand Factor
spellingShingle	dimer oxidoreductase protein variant von Willebrand factor von Willebrand factor Article cell migration clinical article controlled study dimerization down regulation embryo endoplasmic reticulum enzyme activity female gene mutation genotype HEK293 cell line human human cell intracellular space male mutational analysis partial thromboplastin time protein analysis protein domain protein expression protein function protein multimerization protein secretion prothrombin time thrombin time von Willebrand disease wild type genetic transfection genetics mutation HEK293 Cells Humans Mutation Transfection von Willebrand Factor Yin, J Ma, Z Su, J Wang, J.-W Zhao, X Ling, J Bai, X Ouyang, W Wang, Z Yu, Z Ruan, C Mutations in the D1 domain of von Willebrand factor impair their propeptide-dependent multimerization, intracellular trafficking and secretion
description	10.1186/s13045-015-0166-9
author2	SURGERY
author_facet	SURGERY Yin, J Ma, Z Su, J Wang, J.-W Zhao, X Ling, J Bai, X Ouyang, W Wang, Z Yu, Z Ruan, C
format	Article
author	Yin, J Ma, Z Su, J Wang, J.-W Zhao, X Ling, J Bai, X Ouyang, W Wang, Z Yu, Z Ruan, C
author_sort	Yin, J
title	Mutations in the D1 domain of von Willebrand factor impair their propeptide-dependent multimerization, intracellular trafficking and secretion
title_short	Mutations in the D1 domain of von Willebrand factor impair their propeptide-dependent multimerization, intracellular trafficking and secretion
title_full	Mutations in the D1 domain of von Willebrand factor impair their propeptide-dependent multimerization, intracellular trafficking and secretion
title_fullStr	Mutations in the D1 domain of von Willebrand factor impair their propeptide-dependent multimerization, intracellular trafficking and secretion
title_full_unstemmed	Mutations in the D1 domain of von Willebrand factor impair their propeptide-dependent multimerization, intracellular trafficking and secretion
title_sort	mutations in the d1 domain of von willebrand factor impair their propeptide-dependent multimerization, intracellular trafficking and secretion
publishDate	2020
url	https://scholarbank.nus.edu.sg/handle/10635/180908
_version_	1800914614728261632

Mutations in the D1 domain of von Willebrand factor impair their propeptide-dependent multimerization, intracellular trafficking and secretion

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