TEX11 is mutated in infertile men with azoospermia and regulates genome-wide recombination rates in mouse

• Main Authors: Yang, F, Silber, S, Leu, N.A, Oates, R.D, Marszalek, J.D, Skaletsky, H, Brown, L.G, Rozen, S, Page, D.C, Wang, P.J
• Other Authors: DUKE-NUS MEDICAL SCHOOL
• Format: Article
• Published: 2020
• Subjects: chromosome protein; TEX11 protein; unclassified drug; mutant protein; nonhistone protein; TEX11 protein, human; adult; amino acid substitution; animal experiment; animal model; animal tissue; Article; azoospermia; chromosome pairing; controlled study; female; frameshift mutation; gene; gene dosage; gene mutation; genetic screening; human; human tissue; juvenile animal; major clinical study; male; male infertility; meiotic recombination; missense mutation; mouse; nonhuman; pachytene; point mutation; priority journal; spermatogenesis; spermatozoon count; splice site mutation; TEX11 gene; transgenic mouse; X chromosomal inheritance; animal; genetic recombination; genetics; meiosis; mutation; Animals; Azoospermia; Chromosomal Proteins, Non-Histone; Genetic Testing; Humans; Infertility, Male; Male; Meiosis; Mice; Mice, Transgenic; Mutant Proteins; Mutation; Recombination, Genetic
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/180942
• Institution: National University of Singapore

10.15252/emmm.201404967