Decreased miR122 in hepatocellular carcinoma leads to chemoresistance with increased arginine

• Main Authors: Kishikawa, T, Otsuka, M, Tan, P.S, Ohno, M, Sun, X, Yoshikawa, T, Shibata, C, Takata, A, Kojima, K, Takehana, K, Ohishi, M, Ota, S, Noyama, T, Kondo, Y, Sato, M, Soga, T, Hoshida, Y, Koike, K
• Other Authors: MEDICINE
• Format: Article
• Published: 2020
• Subjects: amino acid transporter; arginine; carrier protein; ellipticine; microRNA 122; nitric oxide; nitric oxide synthase; pd 407824; protein kinase inhibitor; sorafenib; unclassified drug; carbanilamide derivative; microRNA; MIRN122 microRNA, human; nicotinamide; animal tissue; Article; cancer resistance; cell level; controlled study; drug screening; drug sensitivity; gene silencing; human; human cell; liver cancer cell line; liver cell carcinoma; mouse; nonhuman; upregulation; analogs and derivatives; animal; apoptosis; biosynthesis; C57BL mouse; Carcinoma, Hepatocellular; deficiency; drug resistance; genetics; Liver Neoplasms; metabolism; pathology; physiology; transgenic mouse; tumor cell line; Animals; Apoptosis; Arginine; Cell Line, Tumor; Drug Resistance, Neoplasm; Humans; Mice; Mice, Inbred C57BL; Mice, Transgenic; MicroRNAs; Niacinamide; Phenylurea Compounds
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/180954
• Institution: National University of Singapore

10.18632/oncotarget.3234