NF-κB signaling mediates acquired resistance after PARP inhibition

10.18632/oncotarget.2868

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Main Authors:	Nakagawa, Y, Sedukhina, A.S, Okamoto, N, Nagasawa, S, Suzuki, N, Ohta, T, Hattori, H, Roche-Molina, M, Narváez, A.J, Jeyasekharan, A.D, Bernal, J.A, Sato, K
Other Authors:	MEDICINE
Format:	Article
Published:	2020
Subjects:	3 (4 methylphenylsulfonyl) 2 propenenitrile bortezomib immunoglobulin enhancer binding protein nicotinamide adenine dinucleotide adenosine diphosphate ribosyltransferase olaparib RNA rucaparib nicotinamide adenine dinucleotide adenosine diphosphate ribosyltransferase inhibitor Article cell death controlled study drug sensitivity enzyme inhibition gene expression human human cell ovary cell RNA sequence signal transduction upregulation antagonists and inhibitors apoptosis Breast Neoplasms drug effects drug resistance female genetics metabolism nucleotide sequence Ovarian Neoplasms pathology tumor cell line tumor suppressor gene Apoptosis Base Sequence Bortezomib Cell Line, Tumor Drug Resistance, Neoplasm Female Genes, BRCA1 Humans NF-kappa B Poly(ADP-ribose) Polymerase Inhibitors Signal Transduction Up-Regulation
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/180961
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Institution:	National University of Singapore

id	sg-nus-scholar.10635-180961
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spelling	sg-nus-scholar.10635-1809612024-11-13T03:12:20Z NF-κB signaling mediates acquired resistance after PARP inhibition Nakagawa, Y Sedukhina, A.S Okamoto, N Nagasawa, S Suzuki, N Ohta, T Hattori, H Roche-Molina, M Narváez, A.J Jeyasekharan, A.D Bernal, J.A Sato, K MEDICINE 3 (4 methylphenylsulfonyl) 2 propenenitrile bortezomib immunoglobulin enhancer binding protein nicotinamide adenine dinucleotide adenosine diphosphate ribosyltransferase olaparib RNA rucaparib immunoglobulin enhancer binding protein nicotinamide adenine dinucleotide adenosine diphosphate ribosyltransferase inhibitor Article cell death controlled study drug sensitivity enzyme inhibition gene expression human human cell ovary cell RNA sequence signal transduction upregulation antagonists and inhibitors apoptosis Breast Neoplasms drug effects drug resistance female genetics metabolism nucleotide sequence Ovarian Neoplasms pathology signal transduction tumor cell line tumor suppressor gene Apoptosis Base Sequence Bortezomib Breast Neoplasms Cell Line, Tumor Drug Resistance, Neoplasm Female Genes, BRCA1 Humans NF-kappa B Ovarian Neoplasms Poly(ADP-ribose) Polymerase Inhibitors Signal Transduction Up-Regulation 10.18632/oncotarget.2868 Oncotarget 6 6 3825-3839 2020-10-27T05:52:52Z 2020-10-27T05:52:52Z 2015 Article Nakagawa, Y, Sedukhina, A.S, Okamoto, N, Nagasawa, S, Suzuki, N, Ohta, T, Hattori, H, Roche-Molina, M, Narváez, A.J, Jeyasekharan, A.D, Bernal, J.A, Sato, K (2015). NF-κB signaling mediates acquired resistance after PARP inhibition. Oncotarget 6 (6) : 3825-3839. ScholarBank@NUS Repository. https://doi.org/10.18632/oncotarget.2868 19492553 https://scholarbank.nus.edu.sg/handle/10635/180961 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Unpaywall 20201031
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	3 (4 methylphenylsulfonyl) 2 propenenitrile bortezomib immunoglobulin enhancer binding protein nicotinamide adenine dinucleotide adenosine diphosphate ribosyltransferase olaparib RNA rucaparib immunoglobulin enhancer binding protein nicotinamide adenine dinucleotide adenosine diphosphate ribosyltransferase inhibitor Article cell death controlled study drug sensitivity enzyme inhibition gene expression human human cell ovary cell RNA sequence signal transduction upregulation antagonists and inhibitors apoptosis Breast Neoplasms drug effects drug resistance female genetics metabolism nucleotide sequence Ovarian Neoplasms pathology signal transduction tumor cell line tumor suppressor gene Apoptosis Base Sequence Bortezomib Breast Neoplasms Cell Line, Tumor Drug Resistance, Neoplasm Female Genes, BRCA1 Humans NF-kappa B Ovarian Neoplasms Poly(ADP-ribose) Polymerase Inhibitors Signal Transduction Up-Regulation
spellingShingle	3 (4 methylphenylsulfonyl) 2 propenenitrile bortezomib immunoglobulin enhancer binding protein nicotinamide adenine dinucleotide adenosine diphosphate ribosyltransferase olaparib RNA rucaparib immunoglobulin enhancer binding protein nicotinamide adenine dinucleotide adenosine diphosphate ribosyltransferase inhibitor Article cell death controlled study drug sensitivity enzyme inhibition gene expression human human cell ovary cell RNA sequence signal transduction upregulation antagonists and inhibitors apoptosis Breast Neoplasms drug effects drug resistance female genetics metabolism nucleotide sequence Ovarian Neoplasms pathology signal transduction tumor cell line tumor suppressor gene Apoptosis Base Sequence Bortezomib Breast Neoplasms Cell Line, Tumor Drug Resistance, Neoplasm Female Genes, BRCA1 Humans NF-kappa B Ovarian Neoplasms Poly(ADP-ribose) Polymerase Inhibitors Signal Transduction Up-Regulation Nakagawa, Y Sedukhina, A.S Okamoto, N Nagasawa, S Suzuki, N Ohta, T Hattori, H Roche-Molina, M Narváez, A.J Jeyasekharan, A.D Bernal, J.A Sato, K NF-κB signaling mediates acquired resistance after PARP inhibition
description	10.18632/oncotarget.2868
author2	MEDICINE
author_facet	MEDICINE Nakagawa, Y Sedukhina, A.S Okamoto, N Nagasawa, S Suzuki, N Ohta, T Hattori, H Roche-Molina, M Narváez, A.J Jeyasekharan, A.D Bernal, J.A Sato, K
format	Article
author	Nakagawa, Y Sedukhina, A.S Okamoto, N Nagasawa, S Suzuki, N Ohta, T Hattori, H Roche-Molina, M Narváez, A.J Jeyasekharan, A.D Bernal, J.A Sato, K
author_sort	Nakagawa, Y
title	NF-κB signaling mediates acquired resistance after PARP inhibition
title_short	NF-κB signaling mediates acquired resistance after PARP inhibition
title_full	NF-κB signaling mediates acquired resistance after PARP inhibition
title_fullStr	NF-κB signaling mediates acquired resistance after PARP inhibition
title_full_unstemmed	NF-κB signaling mediates acquired resistance after PARP inhibition
title_sort	nf-κb signaling mediates acquired resistance after parp inhibition
publishDate	2020
url	https://scholarbank.nus.edu.sg/handle/10635/180961
_version_	1821193041486020608

NF-κB signaling mediates acquired resistance after PARP inhibition

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