NF-κB signaling mediates acquired resistance after PARP inhibition

10.18632/oncotarget.2868

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Bibliographic Details
Main Authors:	Nakagawa, Y, Sedukhina, A.S, Okamoto, N, Nagasawa, S, Suzuki, N, Ohta, T, Hattori, H, Roche-Molina, M, Narváez, A.J, Jeyasekharan, A.D, Bernal, J.A, Sato, K
Other Authors:	MEDICINE
Format:	Article
Published:	2020
Subjects:	3 (4 methylphenylsulfonyl) 2 propenenitrile bortezomib immunoglobulin enhancer binding protein nicotinamide adenine dinucleotide adenosine diphosphate ribosyltransferase olaparib RNA rucaparib nicotinamide adenine dinucleotide adenosine diphosphate ribosyltransferase inhibitor Article cell death controlled study drug sensitivity enzyme inhibition gene expression human human cell ovary cell RNA sequence signal transduction upregulation antagonists and inhibitors apoptosis Breast Neoplasms drug effects drug resistance female genetics metabolism nucleotide sequence Ovarian Neoplasms pathology tumor cell line tumor suppressor gene Apoptosis Base Sequence Bortezomib Cell Line, Tumor Drug Resistance, Neoplasm Female Genes, BRCA1 Humans NF-kappa B Poly(ADP-ribose) Polymerase Inhibitors Signal Transduction Up-Regulation
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/180961
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Institution:	National University of Singapore

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