NF-κB signaling mediates acquired resistance after PARP inhibition

• Main Authors: Nakagawa, Y, Sedukhina, A.S, Okamoto, N, Nagasawa, S, Suzuki, N, Ohta, T, Hattori, H, Roche-Molina, M, Narváez, A.J, Jeyasekharan, A.D, Bernal, J.A, Sato, K
• Other Authors: MEDICINE
• Format: Article
• Published: 2020
• Subjects: 3 (4 methylphenylsulfonyl) 2 propenenitrile; bortezomib; immunoglobulin enhancer binding protein; nicotinamide adenine dinucleotide adenosine diphosphate ribosyltransferase; olaparib; RNA; rucaparib; nicotinamide adenine dinucleotide adenosine diphosphate ribosyltransferase inhibitor; Article; cell death; controlled study; drug sensitivity; enzyme inhibition; gene expression; human; human cell; ovary cell; RNA sequence; signal transduction; upregulation; antagonists and inhibitors; apoptosis; Breast Neoplasms; drug effects; drug resistance; female; genetics; metabolism; nucleotide sequence; Ovarian Neoplasms; pathology; tumor cell line; tumor suppressor gene; Apoptosis; Base Sequence; Bortezomib; Cell Line, Tumor; Drug Resistance, Neoplasm; Female; Genes, BRCA1; Humans; NF-kappa B; Poly(ADP-ribose) Polymerase Inhibitors; Signal Transduction; Up-Regulation
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/180961

10.18632/oncotarget.2868