Thromboxane A2 is a key regulator of pathogenesis during Trypanosoma cruzi infection

• Main Authors: Ashton, A.W, Mukherjee, S, Nagajyothi, F.N.U, Huang, H, Braunstein, V.L, Desruisseaux, M.S, Factor, S.M, Lopez, L, Berman, J.W, Wittner, M, Scherer, P.E, Capra, V, Coffman, T.M, Serhan, C.N, Gotlinger, K, Wu, K.K, Weiss, L.M, Tanowitz, H.B
• Other Authors: DUKE-NUS MEDICAL SCHOOL
• Format: Article
• Published: 2020
• Subjects: thromboxane A2; thromboxane A2 receptor; thromboxane synthase; guanine nucleotide binding protein alpha subunit; animal cell; animal experiment; animal model; article; controlled study; disease course; disease severity; gene deletion; human; human cell; liquid chromatography; male; mortality; mouse; nonhuman; parasitism; pathogenesis; priority journal; protein expression; tandem mass spectrometry; Trypanosoma cruzi; trypanosomiasis; acute disease; animal; C57BL mouse; cell culture; Chagas disease; genetics; metabolism; mouse mutant; parasitology; pathogenicity; pathology; physiology; signal transduction; Acute Disease; Animals; Cells, Cultured; Chagas Disease; GTP-Binding Protein alpha Subunits, Gq-G11; Humans; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, Thromboxane A2, Prostaglandin H2; Signal Transduction; Thromboxane A2
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/181039
• Institution: National University of Singapore

10.1084/jem.20062432