Durable engraftment of genetically modified FVIII-secreting autologous bone marrow stromal cells in the intramedullary microenvironment

• Main Authors: Lee, S.S, Sivalingam, J, Nirmal, A.J, Ng, W.H, Kee, I, Song, I.C, Kiong, C.Y, Gales, K.A, Chua, F, Pena, E.M, Ogden, B.E, Kon, O.L
• Other Authors: DUKE-NUS MEDICAL SCHOOL
• Format: Article
• Published: 2020
• Subjects: beta1 integrin; blood clotting factor 8; CD14 antigen; CD34 antigen; CD79a antigen; endoglin; Thy 1 membrane glycoprotein; adult; animal cell; animal experiment; animal model; Article; autologous bone marrow transplantation; bone marrow biopsy; bone marrow stroma cell; controlled study; dog; engraftment; enzyme linked immunosorbent assay; flow cytometry; genetic selection; hemophilia A; human; human cell; immunophenotyping; male; microenvironment; nonhuman; plasmid; priority journal; protein expression; tissue microenvironment; transformed cell line
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/181194
• Institution: National University of Singapore

10.1111/jcmm.13648