A polymorphism in the base excision repair gene PARP2 is associated with differential prognosis by chemotherapy among postmenopausal breast cancer patients

• Main Authors: Seibold, P, Schmezer, P, Behrens, S
• Other Authors: SURGERY
• Format: Article
• Published: 2020
• Subjects: anthracycline; guanine; nicotinamide adenine dinucleotide adenosine diphosphate ribosyltransferase 2; antineoplastic agent; nicotinamide adenine dinucleotide adenosine diphosphate ribosyltransferase; PARP2 protein, human; adult; aged; Article; breast cancer; cancer adjuvant therapy; cancer patient; cancer prognosis; cancer radiotherapy; cancer specific survival; controlled study; excision repair; female; gene frequency; gene replication; genetic association; genetic variability; heterozygote; human; major clinical study; middle aged; patient assessment; postmenopause; single nucleotide polymorphism; adjuvant chemotherapy; Breast Neoplasms; genetics; genotype; meta analysis; mortality; prognosis; proportional hazards model; radiotherapy; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Female; Genotype; Humans; Middle Aged; Poly(ADP-ribose) Polymerases; Polymorphism, Single Nucleotide; Postmenopause; Prognosis; Proportional Hazards Models; Radiotherapy
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/181408
• Institution: National University of Singapore

10.1186/s12885-015-1957-7