Integromics network meta-analysis on cardiac aging offers robust multi-layer modular signatures and reveals micronome synergism

• Main Authors: Dimitrakopoulou, K, Vrahatis, A.G, Bezerianos, A
• Other Authors: LIFE SCIENCES INSTITUTE
• Format: Article
• Published: 2020
• Subjects: cytochrome c oxidase; hyperpolarization activated cyclic nucleotide gated potassium channel 3; microRNA; microRNA 106a; microRNA 106b; microRNA 107; microRNA 125a; microRNA 125b; microRNA 128; microRNA 132; microRNA 148a; microRNA 152; microRNA 15b; microRNA 181b; microRNA 18a; microRNA 190b; microRNA 19a; microRNA 200b; microRNA 200c; microRNA 22; microRNA 34a; microRNA 363; potassium channel; proteome; proton transporting adenosine triphosphate synthase; Ras protein; reduced nicotinamide adenine dinucleotide dehydrogenase; ribosome protein; transcriptome; unclassified drug; aging; Article; biomics; cardiac aging; cardiovascular parameters; computer program; human; information processing; integromics; lifespan; longevity; mathematical analysis; nonhuman; protein expression; protein interaction; protein targeting; proteomics; reproducibility; sequence homology; animal; cardiovascular disease; gene regulatory network; genetics; heart; meta analysis; mouse; pathology; pathophysiology; Aging; Animals; Cardiovascular Diseases; Gene Regulatory Networks; Heart; Humans; Mice; MicroRNAs; Transcriptome
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/181413
• Institution: National University of Singapore

10.1186/s12864-015-1256-3