A randomised trial to evaluate the immunogenicity, reactogenicity, and safety of the 10-valent pneumococcal non-typeable Haemophilus influenzae protein D conjugate vaccine (PHiD-CV) co-administered with routine childhood vaccines in Singapore and Malaysia

• Main Authors: Lim, F.S, Koh, M.T, Tan, K.K, Chan, P.C, Chong, C.Y, Shung Yehudi, Y.W, Teoh, Y.L, Shafi, F, Hezareh, M, Swinnen, K, Borys, D
• Other Authors: MEDICINE
• Format: Article
• Published: 2020
• Subjects: 10 valent pneumococcal nontypeable Haemophilus influenzae protein D conjugate vaccine; antipyretic agent; bacterial vaccine; bacterium antibody; diphtheria pertussis poliomyelitis tetanus Haemophilus influenzae type b hepatitis B vaccine; diphtheria pertussis tetanus Haemophilus influenzae type b vaccine; protein D antibody; Rotavirus vaccine; unclassified drug; bacterial polysaccharide; bacterial protein; carrier protein; glpQ protein, Haemophilus influenzae; immunoglobulin D; lipoprotein; Pneumococcus vaccine; vaccine; antibody titer; Article; bacterial immunity; controlled study; coughing; diarrhea; diphtheria; drug safety; female; fever; Haemophilus infection; hepatitis B; human; immunogenicity; infant; irritability; major clinical study; Malaysia; male; multicenter study; pain; parallel design; pertussis; phase 3 clinical trial; pneumococcal infection; poliomyelitis; randomized controlled trial; rhinorrhea; Rotavirus infection; side effect; Singapore; tetanus; upper respiratory tract infection; urticaria; vaccination; blood; clinical trial; immunization; immunology; Pneumococcal Infections; Streptococcus pneumoniae; Antibodies, Bacterial; Bacterial Proteins; Carrier Proteins; Female; Humans; Immunization, Secondary; Immunoglobulin D; Infant; Lipoproteins; Male; Pneumococcal Vaccines; Polysaccharides, Bacterial; Vaccination; Vaccine Potency; Vaccines, Conjugate
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/181484
• Institution: National University of Singapore

10.1186/1471-2334-14-530