Monocyte-derived dendritic cells from HLA-B27+ axial spondyloarthritis (SpA) patients display altered functional capacity and deregulated gene expression

• Main Authors: Talpin, A, Costantino, F, Bonilla, N, Leboime, A, Letourneur, F, Jacques, S, Dumont, F, Amraoui, S, Institut Cochin, INSERM U1016, CNRS (UMR 8104), Université Paris-Descartes, Sorbonne Paris-Cité, 75014, France, Dutertre, C.-A, Garchon, H.-J, Breban, M, Chiocchia
• Other Authors: DUKE-NUS MEDICAL SCHOOL
• Format: Article
• Published: 2020
• Subjects: Escherichia coli lipopolysaccharide; granulocyte macrophage colony stimulating factor; HLA B27 antigen; interleukin 4; metalloproteinase; transcription factor; transcriptome; adamts15 gene; adult; Article; CD4+ T lymphocyte; cell differentiation; cell stimulation; cited2 gene; clinical article; computer model; controlled study; dendritic cell; female; functional status; gene; gene expression profiling; gene expression regulation; genetic correlation; human; human cell; male; microarray analysis; monocyte; real time polymerase chain reaction; spondylarthritis; transcriptomics; Wnt signaling pathway; cytology; DNA microarray; flow cytometry; genetics; immunology; lymphocyte activation; middle aged; mixed lymphocyte culture; spondyloarthropathy; Adult; CD4-Positive T-Lymphocytes; Dendritic Cells; Female; Flow Cytometry; HLA-B27 Antigen; Humans; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Male; Middle Aged; Monocytes; Oligonucleotide Array Sequence Analysis; Real-Time Polymerase Chain Reaction; Spondylarthropathies; Transcriptome
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/181490
• Institution: National University of Singapore

10.1186/s13075-014-0417-0