Differences in the transactivation domains of p53 family members: A computational study

• Main Authors: Mavinahalli, J.N, Madhumalar, A, Beuerman, R.W, Lane, D.P, Verma, C
• Other Authors: DUKE-NUS MEDICAL SCHOOL
• Format: Article
• Published: 2020
• Subjects: ligase; protein MDM2; protein MDMX; protein p300; protein p53; protein p63; protein p73; DNA binding protein; histone acetyltransferase PCAF; isoprotein; nuclear protein; tumor suppressor protein; tumor suppressor protein p73; alpha helix; amino terminal sequence; article; computer simulation; enzyme regulation; hydrophobicity; mathematical analysis; protein conformation; protein domain; protein phosphorylation; protein protein interaction; protein stability; transactivation domain; amino acid sequence; biology; chemical structure; chemistry; genetics; metabolism; molecular genetics; mutation; phosphorylation; protein binding; protein folding; protein secondary structure; protein tertiary structure; thermodynamics; transcription initiation; Amino Acid Sequence; Computational Biology; DNA-Binding Proteins; Hydrophobicity; Models, Molecular; Molecular Sequence Data; Mutation; Nuclear Proteins; p300-CBP Transcription Factors; Phosphorylation; Protein Binding; Protein Folding; Protein Isoforms; Protein Structure, Secondary; Protein Structure, Tertiary; Proto-Oncogene Proteins c-mdm2; Thermodynamics; Transcriptional Activation; Tumor Suppressor Protein p53; Tumor Suppressor Proteins
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/181680
• Institution: National University of Singapore

10.1186/1471-2164-11-S1-S5