Tri-partite complex for axonal transport drug delivery achieves pharmacological effect

• Main Authors: Filler, A.G, Whiteside, G.T, Bacon, M, Frederickson, M, Howe, F.A, Rabinowitz, M.D, Sokoloff, A.J, Deacon, T.W, Abell, C, Munglani, R, Griffiths, J.R, Bell, B.A, Lever, A.M.L
• Other Authors: MEDICINE
• Format: Article
• Published: 2020
• Subjects: aciclovir; dextran; drug antibody; drug carrier; gabapentin; nerve growth factor; polymer; valaciclovir; wheat germ agglutinin; 4 aminobutyric acid; amine; analgesic agent; cyclohexanecarboxylic acid derivative; nanoparticle; animal cell; animal experiment; animal tissue; article; bacteriophage; cell population; central nervous system; chemical bond; controlled study; drug delivery system; drug distribution; drug effect; drug release; drug targeting; latent period; nerve fiber transport; nonhuman; perikaryon; rat; target cell; animal; biological model; cell culture; cell line; chemistry; dose response; half life time; hamster; Macaca; methodology; nerve cell; pain; rabbit; Sprague Dawley rat; ultrastructure; Amines; Analgesics; Animals; Axonal Transport; Cell Line; Cells, Cultured; Cricetinae; Cyclohexanecarboxylic Acids; Dextrans; Dose-Response Relationship, Drug; Drug Delivery Systems; gamma-Aminobutyric Acid; Half-Life; Macaca fascicularis; Models, Neurological; Nanoparticles; Nerve Growth Factor; Neurons; Pain; Polymers; Rabbits; Rats; Rats, Sprague-Dawley; Wheat Germ Agglutinins
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/181683
• Institution: National University of Singapore

10.1186/1471-2202-11-8