Biochemical and structural characterization of the interface mediating interaction between the influenza A virus non-structural protein-1 and a monoclonal antibody

• Main Authors: Wu, J, Mok, C.-K, Chow, V.T.K, Yuan, Y.A, Tan, Y.-J
• Other Authors: BIOLOGY
• Format: Article
• Published: Nature Publishing Group 2020
• Subjects: double stranded RNA; immunoglobulin F(ab) fragment; monoclonal antibody; protein binding; viral protein; virus antigen; A-549 cell line; amino acid sequence; amino acid substitution; animal; binding site; bird; chemistry; dog; genetics; human; Influenza A virus; Influenza A virus (H5N1); MDCK cell line; metabolism; mutation; virology; virus replication; X ray crystallography; A549 Cells; Amino Acid Sequence; Amino Acid Substitution; Animals; Antibodies, Monoclonal; Antigens, Viral; Binding Sites; Birds; Crystallography, X-Ray; Dogs; Humans; Immunoglobulin Fab Fragments; Influenza A Virus, H5N1 Subtype; Madin Darby Canine Kidney Cells; Mutation; Protein Binding; RNA, Double-Stranded; Viral Nonstructural Proteins; Virus Replication
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/182428
• Institution: National University of Singapore

10.1038/srep33382