Pharmacogenetics-Guided Phase i Study of Capecitabine on an Intermittent Schedule in Patients with Advanced or Metastatic Solid Tumours
10.1038/srep27826
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sg-nus-scholar.10635-1824602024-11-15T08:50:46Z Pharmacogenetics-Guided Phase i Study of Capecitabine on an Intermittent Schedule in Patients with Advanced or Metastatic Solid Tumours Soo, R.A Syn, N Lee, S.-C Wang, L Lim, X.-Y Loh, M Tan, S.-H Zee, Y.-K Wong, A.L.-A Chuah, B Chan, D Lim, S.-E Goh, B.-C Soong, R Yong, W.-P PHARMACOLOGY MEDICINE CANCER SCIENCE INSTITUTE OF SINGAPORE PATHOLOGY antineoplastic agent capecitabine thymidylate synthase adult aged breast tumor cancer staging clinical protocol clinical trial colorectal tumor dose calculation enhancer region female genetic polymorphism genetics genotype human male maximum tolerated dose metastasis middle aged multicenter study pathology pharmacogenetic testing phase 1 clinical trial Adult Aged Antineoplastic Agents Breast Neoplasms Capecitabine Clinical Protocols Colorectal Neoplasms Drug Dosage Calculations Enhancer Elements, Genetic Female Genotype Humans Male Maximum Tolerated Dose Middle Aged Neoplasm Metastasis Neoplasm Staging Pharmacogenomic Testing Polymorphism, Genetic Thymidylate Synthase 10.1038/srep27826 Scientific Reports 6 27826 2020-10-31T11:32:25Z 2020-10-31T11:32:25Z 2016 Article Soo, R.A, Syn, N, Lee, S.-C, Wang, L, Lim, X.-Y, Loh, M, Tan, S.-H, Zee, Y.-K, Wong, A.L.-A, Chuah, B, Chan, D, Lim, S.-E, Goh, B.-C, Soong, R, Yong, W.-P (2016). Pharmacogenetics-Guided Phase i Study of Capecitabine on an Intermittent Schedule in Patients with Advanced or Metastatic Solid Tumours. Scientific Reports 6 : 27826. ScholarBank@NUS Repository. https://doi.org/10.1038/srep27826 2045-2322 https://scholarbank.nus.edu.sg/handle/10635/182460 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Nature Publishing Group Unpaywall 20201031 |
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antineoplastic agent capecitabine thymidylate synthase adult aged breast tumor cancer staging clinical protocol clinical trial colorectal tumor dose calculation enhancer region female genetic polymorphism genetics genotype human male maximum tolerated dose metastasis middle aged multicenter study pathology pharmacogenetic testing phase 1 clinical trial Adult Aged Antineoplastic Agents Breast Neoplasms Capecitabine Clinical Protocols Colorectal Neoplasms Drug Dosage Calculations Enhancer Elements, Genetic Female Genotype Humans Male Maximum Tolerated Dose Middle Aged Neoplasm Metastasis Neoplasm Staging Pharmacogenomic Testing Polymorphism, Genetic Thymidylate Synthase |
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antineoplastic agent capecitabine thymidylate synthase adult aged breast tumor cancer staging clinical protocol clinical trial colorectal tumor dose calculation enhancer region female genetic polymorphism genetics genotype human male maximum tolerated dose metastasis middle aged multicenter study pathology pharmacogenetic testing phase 1 clinical trial Adult Aged Antineoplastic Agents Breast Neoplasms Capecitabine Clinical Protocols Colorectal Neoplasms Drug Dosage Calculations Enhancer Elements, Genetic Female Genotype Humans Male Maximum Tolerated Dose Middle Aged Neoplasm Metastasis Neoplasm Staging Pharmacogenomic Testing Polymorphism, Genetic Thymidylate Synthase Soo, R.A Syn, N Lee, S.-C Wang, L Lim, X.-Y Loh, M Tan, S.-H Zee, Y.-K Wong, A.L.-A Chuah, B Chan, D Lim, S.-E Goh, B.-C Soong, R Yong, W.-P Pharmacogenetics-Guided Phase i Study of Capecitabine on an Intermittent Schedule in Patients with Advanced or Metastatic Solid Tumours |
| description |
10.1038/srep27826 |
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PHARMACOLOGY |
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PHARMACOLOGY Soo, R.A Syn, N Lee, S.-C Wang, L Lim, X.-Y Loh, M Tan, S.-H Zee, Y.-K Wong, A.L.-A Chuah, B Chan, D Lim, S.-E Goh, B.-C Soong, R Yong, W.-P |
| format |
Article |
| author |
Soo, R.A Syn, N Lee, S.-C Wang, L Lim, X.-Y Loh, M Tan, S.-H Zee, Y.-K Wong, A.L.-A Chuah, B Chan, D Lim, S.-E Goh, B.-C Soong, R Yong, W.-P |
| author_sort |
Soo, R.A |
| title |
Pharmacogenetics-Guided Phase i Study of Capecitabine on an Intermittent Schedule in Patients with Advanced or Metastatic Solid Tumours |
| title_short |
Pharmacogenetics-Guided Phase i Study of Capecitabine on an Intermittent Schedule in Patients with Advanced or Metastatic Solid Tumours |
| title_full |
Pharmacogenetics-Guided Phase i Study of Capecitabine on an Intermittent Schedule in Patients with Advanced or Metastatic Solid Tumours |
| title_fullStr |
Pharmacogenetics-Guided Phase i Study of Capecitabine on an Intermittent Schedule in Patients with Advanced or Metastatic Solid Tumours |
| title_full_unstemmed |
Pharmacogenetics-Guided Phase i Study of Capecitabine on an Intermittent Schedule in Patients with Advanced or Metastatic Solid Tumours |
| title_sort |
pharmacogenetics-guided phase i study of capecitabine on an intermittent schedule in patients with advanced or metastatic solid tumours |
| publisher |
Nature Publishing Group |
| publishDate |
2020 |
| url |
https://scholarbank.nus.edu.sg/handle/10635/182460 |
| _version_ |
1821233185713815552 |