Endothelin-1 supports clonal derivation and expansion of cardiovascular progenitors derived from human embryonic stem cells

• Main Authors: Soh, B.-S, Ng, S.-Y, Wu, H, Buac, K, Park, J.-H.C, Lian, X, Xu, J, Foo, K.S, Felldin, U, He, X, Nichane, M, Yang, H, Bu, L, Li, R.A, Lim, B, Chien, K.R
• Other Authors: MICROBIOLOGY AND IMMUNOLOGY
• Format: Article
• Published: Nature Publishing Group 2020
• Subjects: endothelin 1; growth factor receptor; protein kinase B; recombinant protein; Wnt3a protein; insulin gene enhancer binding protein Isl-1; LIM homeodomain protein; transcription factor; biological development; cardiovascular system; cells and cell components; clonal growth; embryo; muscle; protein; adult; angiogenesis; animal cell; animal experiment; animal model; animal tissue; Article; cardiovascular progenitor cell; cell differentiation; cell isolation; cell lineage; chimera; clonal variation; controlled study; endothelium cell; fetal stem cell; fetus; fetus heart; gene expression; heart infarction; human; human cell; human embryonic stem cell; immunofluorescence test; in vitro study; in vivo study; mouse; multipotent stem cell; nonhuman; smooth muscle fiber; stem cell; stem cell expansion; stem cell transplantation; animal; cardiac muscle cell; cell proliferation; cytology; genetics; growth, development and aging; male; metabolism; nonobese diabetic mouse; Animals; Cardiovascular System; Cell Differentiation; Cell Proliferation; Endothelin-1; Human Embryonic Stem Cells; Humans; LIM-Homeodomain Proteins; Male; Mice; Mice, Inbred NOD; Myocytes, Cardiac; Transcription Factors
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/182495
• Institution: National University of Singapore

10.1038/ncomms10774