Longitudinal metabolic imaging of hepatocellular carcinoma in transgenic mouse models identifies acylcarnitine as a potential biomarker for early detection

• Main Authors: Yaligar, J, Teoh, W.W, Othman, R, Verma, S.K, Phang, B.H, Lee, S.S, Wang, W.W, Toh, H.C, Gopalan, V, Sabapathy, K, Velan, S.S
• Other Authors: MEDICINE
• Format: Article
• Published: Nature Publishing Group 2020
• Subjects: acylcarnitine; biological marker; carnitine; analogs and derivatives; animal; blood; Carcinoma, Hepatocellular; diffusion weighted imaging; disease model; early cancer diagnosis; gene expression profiling; genetics; human; Liver Neoplasms; metabolism; molecular imaging; mouse; procedures; transgenic mouse; tumor volume; Animals; Biomarkers; Carnitine; Diffusion Magnetic Resonance Imaging; Disease Models, Animal; Early Detection of Cancer; Gene Expression Profiling; Humans; Mice; Mice, Transgenic; Molecular Imaging; Tumor Burden
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/182509
• Institution: National University of Singapore

10.1038/srep20299