High-risk HPV genotypes and P16INK4a expression in a cohort of head and neck squamous cell carcinoma patients in Singapore

• Main Authors: Tan, L.S.Y, Fredrik, P, Ker, L, Yu, F.G, Wang, D.Y, Goh, B.C, Loh, K.S, Lim, C.M
• Other Authors: OTOLARYNGOLOGY
• Format: Article
• Published: Impact Journals LLC 2020
• Subjects: cyclin dependent kinase inhibitor 2A; DNA; protein p16; virus DNA; adult; alcohol consumption; Article; cancer prognosis; cancer risk; cancer specific survival; cancer tissue; clinical outcome; cohort analysis; controlled study; female; genotype; head and neck squamous cell carcinoma; human; human cell; Human papillomavirus type 16; Human papillomavirus type 18; Human papillomavirus type 31; Human papillomavirus type 45; Human papillomavirus type 56; Human papillomavirus type 68; human tissue; immunohistochemistry; intermethod comparison; major clinical study; male; nonhuman; oropharynx squamous cell carcinoma; overall survival; polymerase chain reaction; prevalence; protein expression; reliability; sensitivity and specificity; Singapore; smoking; survival rate; survival time; virus carcinogenesis; virus detection; virus identification; Wart virus; Asian continental ancestry group; biosynthesis; ethnology; genetics; head and neck tumor; host pathogen interaction; Kaplan Meier method; metabolism; middle aged; oropharynx tumor; Papillomaviridae; papillomavirus infection; squamous cell carcinoma; virology; young adult; Adult; Asian Continental Ancestry Group; Carcinoma, Squamous Cell; Cohort Studies; Cyclin-Dependent Kinase Inhibitor p16; Female; Genotype; Head and Neck Neoplasms; Host-Pathogen Interactions; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Oropharyngeal Neoplasms; Papillomavirus Infections; Young Adult
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/182519
• Institution: National University of Singapore

10.18632/oncotarget.13502