Effects of naltrexone are influenced by childhood adversity during negative emotional processing in addiction recovery

• Main Authors: Savulich, G, Riccelli, R, Passamonti, L, Correia, M, Deakin, J.F.W, Elliott, R, Flechais, R.S.A, Lingford-Hughes, A.R, McGonigle, J, Murphy, A, Nutt, D.J, Orban, C, Paterson, L.M, Reed, L.J, Smith, D.G, Suckling, J, Tait, R, Taylor, E.M, Sahakian, B.J, Robbins, T.W, Ersche, K.D
• Other Authors: DEPT OF ELECTRICAL & COMPUTER ENGG
• Format: Article
• Published: Springer Nature 2020
• Subjects: naltrexone; placebo; narcotic antagonist; adult; alcoholism; anterior cingulate; Article; aversive behavior; controlled study; crossover procedure; double blind procedure; drug dependence; emotion; environmental factor; female; functional connectivity; functional magnetic resonance imaging; hippocampus; human; male; medial prefrontal cortex; randomized controlled trial; amygdala; association; brain; case control study; childhood trauma survivor; cingulate gyrus; cocaine dependence; diagnostic imaging; drug effects; functional neuroimaging; middle aged; nerve tract; nuclear magnetic resonance imaging; opiate addiction; pathophysiology; prefrontal cortex; young adult; Adult; Adult Survivors of Child Adverse Events; Alcoholism; Amygdala; Brain; Case-Control Studies; Cocaine-Related Disorders; Cross-Over Studies; Cues; Double-Blind Method; Female; Functional Neuroimaging; Gyrus Cinguli; Hippocampus; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Naltrexone; Narcotic Antagonists; Neural Pathways; Opioid-Related Disorders; Prefrontal Cortex; Substance-Related Disorders; Young Adult
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/183541
• Institution: National University of Singapore

10.1038/tp.2017.34