Pharmacological utilization of bergamottin, derived from grapefruits, in cancer prevention and therapy

• Main Authors: Ko, J.-H, Arfuso, F, Sethi, G, Ahn, K.S
• Other Authors: DEPT OF PHARMACOLOGY
• Published: MDPI 2020
• Subjects: bergamottin; cytochrome P450; etoposide; furocoumarin; nilotinib; plant medicinal product; polycyclic aromatic hydrocarbon; sunitinib; antiinflammatory agent; cytochrome P450 inhibitor; furocoumarin derivative; antiinflammatory activity; antineoplastic activity; antioxidant activity; antiproliferative activity; apoptosis; bioavailability; cancer growth; cancer inhibition; cancer prevention; cancer therapy; carcinogenesis; cell migration; cell proliferation; chemoprophylaxis; cytotoxicity; fibrosarcoma; grapefruit; leukemia; liver cell carcinoma; lung cancer; multiple myeloma; nonhuman; phosphorylation; plant metabolism; Review; signal transduction; skin cancer; tumor growth; chemical structure; chemistry; drug effect; human; metabolism; neoplasm; oxidative stress; Anti-Inflammatory Agents; Citrus paradisi; Cytochrome P-450 Enzyme Inhibitors; Furocoumarins; Humans; Molecular Structure; Neoplasms; Oxidative Stress
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/183824
• Institution: National University of Singapore

10.3390/ijms19124048