Disrupted muscarinic M-1 receptor signaling correlates with loss of protein kinase C activity and glutamatergic deficit in Alzheimer's disease

• Main Authors: Tsang, Shirley WY, Pomakian, Justine, Marshall, Gad A, Vinters, Harry V, Cummings, Jeffrey L, Chen, Christopher PL-H, Wong, Peter T-H, Lai, Mitchell KP
• Other Authors: DEPT OF PHARMACOLOGY
• Format: Article
• Language: English
• Published: ELSEVIER SCIENCE INC 2021
• Subjects: Science & Technology; Life Sciences & Biomedicine; Geriatrics & Gerontology; Neurosciences; Neurosciences & Neurology; muscarinic receptors; glutamate receptors; protein kinase C; Src kinase; neocortex; CHOLINERGIC HYPOTHESIS; TRANSGENIC MICE; NMDA RECEPTORS/; PKC ACTIVATORS; EXPRESSION; DEMENTIA; BINDING; PHOSPHORYLATION; BRAIN; TRANSMISSION
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/188373
• Institution: National University of Singapore

10.1016/j.neurobiolaging.2006.06.001