Hiltonol Cocktail Kills Lung Cancer Cells by Activating Cancer-Suppressors, PKR/OAS, and Restraining the Tumor Microenvironment

10.3390/ijms22041626

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Main Authors: Chang, Shu-Chun, Zhang, Bo-Xiang, Su, Emily Chia-Yu, Wu, Wei-Ciao, Hsieh, Tsung-Han, Salazar, Andres M, Lin, Yen-Kuang, Ding, Jeak Ling
Other Authors: BIOLOGICAL SCIENCES
Format: Article
Language:English
Published: MDPI 2021
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Online Access:https://scholarbank.nus.edu.sg/handle/10635/193720
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Institution: National University of Singapore
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spelling sg-nus-scholar.10635-1937202024-04-03T06:27:25Z Hiltonol Cocktail Kills Lung Cancer Cells by Activating Cancer-Suppressors, PKR/OAS, and Restraining the Tumor Microenvironment Chang, Shu-Chun Zhang, Bo-Xiang Su, Emily Chia-Yu Wu, Wei-Ciao Hsieh, Tsung-Han Salazar, Andres M Lin, Yen-Kuang Ding, Jeak Ling BIOLOGICAL SCIENCES Science & Technology Life Sciences & Biomedicine Physical Sciences Biochemistry & Molecular Biology Chemistry, Multidisciplinary Chemistry NSCLC (non-small cell lung cancer) combinatorial treatment with Hiltonol(+++) cocktail [Hiltonol+anti-IL6+stattic+AG490] tumorigenic microenvironment anti and pro-tumorigenic cytokine production tumor-suppressors PKR (protein kinase R) and OAS (2′ 5′ oligoadenylate synthetase) 10.3390/ijms22041626 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 22 4 2021-07-06T10:54:23Z 2021-07-06T10:54:23Z 2021-02-01 2021-07-06T07:36:48Z Article Chang, Shu-Chun, Zhang, Bo-Xiang, Su, Emily Chia-Yu, Wu, Wei-Ciao, Hsieh, Tsung-Han, Salazar, Andres M, Lin, Yen-Kuang, Ding, Jeak Ling (2021-02-01). Hiltonol Cocktail Kills Lung Cancer Cells by Activating Cancer-Suppressors, PKR/OAS, and Restraining the Tumor Microenvironment. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 22 (4). ScholarBank@NUS Repository. https://doi.org/10.3390/ijms22041626 16616596 14220067 https://scholarbank.nus.edu.sg/handle/10635/193720 en MDPI Elements
institution National University of Singapore
building NUS Library
continent Asia
country Singapore
Singapore
content_provider NUS Library
collection ScholarBank@NUS
language English
topic Science & Technology
Life Sciences & Biomedicine
Physical Sciences
Biochemistry & Molecular Biology
Chemistry, Multidisciplinary
Chemistry
NSCLC (non-small cell lung cancer)
combinatorial treatment with Hiltonol(+++) cocktail [Hiltonol+anti-IL6+stattic+AG490]
tumorigenic microenvironment
anti
and pro-tumorigenic cytokine production
tumor-suppressors PKR (protein kinase R) and OAS (2′
5′
oligoadenylate synthetase)
spellingShingle Science & Technology
Life Sciences & Biomedicine
Physical Sciences
Biochemistry & Molecular Biology
Chemistry, Multidisciplinary
Chemistry
NSCLC (non-small cell lung cancer)
combinatorial treatment with Hiltonol(+++) cocktail [Hiltonol+anti-IL6+stattic+AG490]
tumorigenic microenvironment
anti
and pro-tumorigenic cytokine production
tumor-suppressors PKR (protein kinase R) and OAS (2′
5′
oligoadenylate synthetase)
Chang, Shu-Chun
Zhang, Bo-Xiang
Su, Emily Chia-Yu
Wu, Wei-Ciao
Hsieh, Tsung-Han
Salazar, Andres M
Lin, Yen-Kuang
Ding, Jeak Ling
Hiltonol Cocktail Kills Lung Cancer Cells by Activating Cancer-Suppressors, PKR/OAS, and Restraining the Tumor Microenvironment
description 10.3390/ijms22041626
author2 BIOLOGICAL SCIENCES
author_facet BIOLOGICAL SCIENCES
Chang, Shu-Chun
Zhang, Bo-Xiang
Su, Emily Chia-Yu
Wu, Wei-Ciao
Hsieh, Tsung-Han
Salazar, Andres M
Lin, Yen-Kuang
Ding, Jeak Ling
format Article
author Chang, Shu-Chun
Zhang, Bo-Xiang
Su, Emily Chia-Yu
Wu, Wei-Ciao
Hsieh, Tsung-Han
Salazar, Andres M
Lin, Yen-Kuang
Ding, Jeak Ling
author_sort Chang, Shu-Chun
title Hiltonol Cocktail Kills Lung Cancer Cells by Activating Cancer-Suppressors, PKR/OAS, and Restraining the Tumor Microenvironment
title_short Hiltonol Cocktail Kills Lung Cancer Cells by Activating Cancer-Suppressors, PKR/OAS, and Restraining the Tumor Microenvironment
title_full Hiltonol Cocktail Kills Lung Cancer Cells by Activating Cancer-Suppressors, PKR/OAS, and Restraining the Tumor Microenvironment
title_fullStr Hiltonol Cocktail Kills Lung Cancer Cells by Activating Cancer-Suppressors, PKR/OAS, and Restraining the Tumor Microenvironment
title_full_unstemmed Hiltonol Cocktail Kills Lung Cancer Cells by Activating Cancer-Suppressors, PKR/OAS, and Restraining the Tumor Microenvironment
title_sort hiltonol cocktail kills lung cancer cells by activating cancer-suppressors, pkr/oas, and restraining the tumor microenvironment
publisher MDPI
publishDate 2021
url https://scholarbank.nus.edu.sg/handle/10635/193720
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