Polysulfide-mediated sulfhydration of SIRT1 prevents diabetic nephropathy by suppressing phosphorylation and acetylation of p65 NF-kappa B and STAT3

• Main Authors: Sun, Hai-Jian, Xiong, Si-Ping, Cao, Xu, Cao, Lei, Zhu, Meng-Yuan, Wu, Zhi-Yuan, Bian, Jin-Song
• Other Authors: PHARMACOLOGY
• Format: Article
• Language: English
• Published: ELSEVIER 2022
• Subjects: Science & Technology; Life Sciences & Biomedicine; Biochemistry & Molecular Biology; Diabetic nephropathy; Reactive oxygen species; Polysulfides; Hydrogen sulfide; SIRT1; HYDROGEN-SULFIDE H2S; OXIDATIVE STRESS; RENAL FIBROSIS; KIDNEY-DISEASE; SULFANE SULFUR; NITRIC-OXIDE; INFLAMMATION; METABOLISM; APOPTOSIS; PATHWAY
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/219267
• Institution: National University of Singapore

10.1016/j.redox.2020.101813