Loss of ULK1 increases RPS6KB1-NCOR1 repression of NR1H/LXR-mediated Scd1 transcription and augments lipotoxicity in hepatic cells

• Main Authors: Sinha, Rohit Anthony, Singh, Brijesh K, Zhou, Jin, Xie, Sherwin, Farah, Benjamin L, Lesmana, Ronny, Ohba, Kenji, Tripathi, Madhulika, Ghosh, Sujoy, Hollenberg, Anthony N, Yen, Paul M
• Other Authors: DEAN'S OFFICE (DUKE-NUS MEDICAL SCHOOL)
• Format: Article
• Language: English
• Published: TAYLOR & FRANCIS INC 2022
• Subjects: Science & Technology; Life Sciences & Biomedicine; Cell Biology; autophagy; lipid droplets; lipotoxicity; LXR; NASH; NCOR1; RPS6KB1; SCD1; ULK1; ENDOPLASMIC-RETICULUM STRESS; FATTY-ACIDS; LIPID-METABOLISM; SKELETAL-MUSCLE; PALMITIC ACID; NONALCOHOLIC STEATOHEPATITIS; AUTOPHAGOSOME BIOGENESIS; INSULIN-RESISTANCE; ENDOTHELIAL-CELLS; MAMMALIAN TARGET
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/226766
• Institution: National University of Singapore

10.1080/15548627.2016.1235123