Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme

10.7554/eLife.33572

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Main Authors: Zhang, Zhening, Liang, Wenguang G, Bailey, Lucas J, Tan, Yong Zi, Wei, Hui, Wang, Andrew, Farcasanu, Mara, Woods, Virgil A, McCord, Lauren A, Lee, David, Shane, Weifeng, Deprez-Poulain, Rebecca, Deprez, Benoit, Liu, David R, Koide, Akiko, Koide, Shohei, Kossiakoff, Anthony A, Li, Sheng, Carragher, Bridget, Potter, Clinton S, Tang, Wei-Jen
Other Authors: BIOLOGICAL SCIENCES
Format: Article
Language:English
Published: ELIFE SCIENCES PUBLICATIONS LTD 2022
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Online Access:https://scholarbank.nus.edu.sg/handle/10635/227217
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Institution: National University of Singapore
Language: English
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spelling sg-nus-scholar.10635-2272172024-04-02T08:13:23Z Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme Zhang, Zhening Liang, Wenguang G Bailey, Lucas J Tan, Yong Zi Wei, Hui Wang, Andrew Farcasanu, Mara Woods, Virgil A McCord, Lauren A Lee, David Shane, Weifeng Deprez-Poulain, Rebecca Deprez, Benoit Liu, David R Koide, Akiko Koide, Shohei Kossiakoff, Anthony A Li, Sheng Carragher, Bridget Potter, Clinton S Tang, Wei-Jen BIOLOGICAL SCIENCES Science & Technology Life Sciences & Biomedicine Biology Life Sciences & Biomedicine - Other Topics EXCHANGE-MASS-SPECTROMETRY BEAM-INDUCED MOTION X-RAY SOLUTION CONFORMATIONAL-CHANGES BIOLOGICAL MACROMOLECULES SUBSTRATE RECOGNITION MOLECULAR-BASIS EM STRUCTURE PROTEIN INHIBITORS 10.7554/eLife.33572 ELIFE 7 2022-06-20T23:55:09Z 2022-06-20T23:55:09Z 2018-03-29 2022-06-18T15:00:14Z Article Zhang, Zhening, Liang, Wenguang G, Bailey, Lucas J, Tan, Yong Zi, Wei, Hui, Wang, Andrew, Farcasanu, Mara, Woods, Virgil A, McCord, Lauren A, Lee, David, Shane, Weifeng, Deprez-Poulain, Rebecca, Deprez, Benoit, Liu, David R, Koide, Akiko, Koide, Shohei, Kossiakoff, Anthony A, Li, Sheng, Carragher, Bridget, Potter, Clinton S, Tang, Wei-Jen (2018-03-29). Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme. ELIFE 7. ScholarBank@NUS Repository. https://doi.org/10.7554/eLife.33572 2050084X https://scholarbank.nus.edu.sg/handle/10635/227217 en ELIFE SCIENCES PUBLICATIONS LTD Elements
institution National University of Singapore
building NUS Library
continent Asia
country Singapore
Singapore
content_provider NUS Library
collection ScholarBank@NUS
language English
topic Science & Technology
Life Sciences & Biomedicine
Biology
Life Sciences & Biomedicine - Other Topics
EXCHANGE-MASS-SPECTROMETRY
BEAM-INDUCED MOTION
X-RAY SOLUTION
CONFORMATIONAL-CHANGES
BIOLOGICAL MACROMOLECULES
SUBSTRATE RECOGNITION
MOLECULAR-BASIS
EM STRUCTURE
PROTEIN
INHIBITORS
spellingShingle Science & Technology
Life Sciences & Biomedicine
Biology
Life Sciences & Biomedicine - Other Topics
EXCHANGE-MASS-SPECTROMETRY
BEAM-INDUCED MOTION
X-RAY SOLUTION
CONFORMATIONAL-CHANGES
BIOLOGICAL MACROMOLECULES
SUBSTRATE RECOGNITION
MOLECULAR-BASIS
EM STRUCTURE
PROTEIN
INHIBITORS
Zhang, Zhening
Liang, Wenguang G
Bailey, Lucas J
Tan, Yong Zi
Wei, Hui
Wang, Andrew
Farcasanu, Mara
Woods, Virgil A
McCord, Lauren A
Lee, David
Shane, Weifeng
Deprez-Poulain, Rebecca
Deprez, Benoit
Liu, David R
Koide, Akiko
Koide, Shohei
Kossiakoff, Anthony A
Li, Sheng
Carragher, Bridget
Potter, Clinton S
Tang, Wei-Jen
Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme
description 10.7554/eLife.33572
author2 BIOLOGICAL SCIENCES
author_facet BIOLOGICAL SCIENCES
Zhang, Zhening
Liang, Wenguang G
Bailey, Lucas J
Tan, Yong Zi
Wei, Hui
Wang, Andrew
Farcasanu, Mara
Woods, Virgil A
McCord, Lauren A
Lee, David
Shane, Weifeng
Deprez-Poulain, Rebecca
Deprez, Benoit
Liu, David R
Koide, Akiko
Koide, Shohei
Kossiakoff, Anthony A
Li, Sheng
Carragher, Bridget
Potter, Clinton S
Tang, Wei-Jen
format Article
author Zhang, Zhening
Liang, Wenguang G
Bailey, Lucas J
Tan, Yong Zi
Wei, Hui
Wang, Andrew
Farcasanu, Mara
Woods, Virgil A
McCord, Lauren A
Lee, David
Shane, Weifeng
Deprez-Poulain, Rebecca
Deprez, Benoit
Liu, David R
Koide, Akiko
Koide, Shohei
Kossiakoff, Anthony A
Li, Sheng
Carragher, Bridget
Potter, Clinton S
Tang, Wei-Jen
author_sort Zhang, Zhening
title Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme
title_short Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme
title_full Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme
title_fullStr Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme
title_full_unstemmed Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme
title_sort ensemble cryoem elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme
publisher ELIFE SCIENCES PUBLICATIONS LTD
publishDate 2022
url https://scholarbank.nus.edu.sg/handle/10635/227217
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