A polygenic risk score improves risk stratification of coronary artery disease: a large-scale prospective Chinese cohort study

• Main Authors: Lu, Xiangfeng, Liu, Zhongying, Cui, Qingmei, Liu, Fangchao, Li, Jianxin, Niu, Xiaoge, Shen, Chong, Hu, Dongsheng, Huang, Keyong, Chen, Jichun, Xing, Xiaolong, Zhao, Yingxin, Lu, Fanghong, Liu, Xiaoqing, Cao, Jie, Chen, Shufeng, Ma, Hongxia, Yu, Ling, Wu, Xianping, Wu, Xigui, Li, Ying, Zhang, Huan, Mo, Xingbo, Zhao, Liancheng, Huang, Jianfeng, Wang, Laiyuan, Wen, Wanqing, Shu, Xiao-Ou, Takeuchi, Fumihiko, Koh, Woon-Puay, Tai, E Shyong, Cheng, Ching-Yu, Wong, Tien Yin, Chang, Xuling, Chan, Mark Yan-Yee, Gao, Wei, Zheng, Hong, Chen, Kexin, Chen, Jing, He, Jiang, Tang, Clara Sze-Man, Lam, Karen Siu Ling, Tse, Hung-Fat, Cheung, Chloe Yu Yan, Takahashi, Atsushi, Kubo, Michiaki, Kato, Norihiro, Terao, Chikashi, Kamatani, Yoichiro, Sham, Pak Chung, Heng, Chew-Kiat, Hu, Zhibin, Chen, Y Eugene, Wu, Tangchun, Shen, Hongbing, Willer, Cristen J, Gu, Dongfeng
• Other Authors: DEAN'S OFFICE (MEDICINE)
• Format: Article
• Language: English
• Published: OXFORD UNIV PRESS 2022
• Subjects: Science & Technology; Life Sciences & Biomedicine; Cardiac & Cardiovascular Systems; Cardiovascular System & Cardiology; Coronary artery disease; Polygenic risk score; Clinical risk score; ATHEROSCLEROTIC CARDIOVASCULAR-DISEASE; GENETIC RISK; PREDICTIVE ACCURACY; EUROPEAN-SOCIETY; MODEL; ASSOCIATION; POPULATION; PREVENTION; GUIDELINES; CARDIOLOGY
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/228337
• Institution: National University of Singapore

10.1093/eurheartj/ehac093