An improved synthesis of n-(4-[18 f]fluorobenzoyl)-interleukin-2 for the preclinical pet imaging of tumour-infiltrating t-cells in ct26 and mc38 colon cancer models

• Main Authors: Khanapur, Shivashankar, Yong, Fui Fong, Hartimath, Siddesh, V, Jiang, Lingfan, Ramasamy, Boominathan, Cheng, Peter, Narayanaswamy, Pradeep, Goggi, Julian L., Robins, Edward George
• Other Authors: DEAN'S OFFICE (MEDICINE)
• Format: Article
• Published: MDPI AG 2022
• Subjects: Interleukin-2 (IL-2); Murine colon adenocarcinoma (MC38 and CT26) syngeneic models; Positron emission tomography (PET) imaging; Protein conjugation reaction; Scintomics GRP™ module; T-cells; [18 F]FB-IL-2; [18 F]SFB
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/232120
• Institution: National University of Singapore

10.3390/molecules26061728