Dl-3-n-Butylphthalide Rescues Dopaminergic Neurons in Parkinson’s Disease Models by Inhibiting the NLRP3 Inflammasome and Ameliorating Mitochondrial Impairment

10.3389/fimmu.2021.794770

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Main Authors: Que, Rongfang, Zheng, Jialing, Chang, Zihan, Zhang, Wenjie, Li, Hualing, Xie, Zhenchao, Huang, Zifeng, Wang, Hai-Tao, Xu, Jiangping, Jin, Dana, Yang, Wanlin, Tan, Eng-King, Wang, Qing
Other Authors: DUKE-NUS MEDICAL SCHOOL
Format: Article
Published: Frontiers Media S.A. 2022
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Online Access:https://scholarbank.nus.edu.sg/handle/10635/232274
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Institution: National University of Singapore
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spelling sg-nus-scholar.10635-2322742024-11-08T18:34:52Z Dl-3-n-Butylphthalide Rescues Dopaminergic Neurons in Parkinson’s Disease Models by Inhibiting the NLRP3 Inflammasome and Ameliorating Mitochondrial Impairment Que, Rongfang Zheng, Jialing Chang, Zihan Zhang, Wenjie Li, Hualing Xie, Zhenchao Huang, Zifeng Wang, Hai-Tao Xu, Jiangping Jin, Dana Yang, Wanlin Tan, Eng-King Wang, Qing DUKE-NUS MEDICAL SCHOOL dl-3-n-Butylphthalide mitochondrial dysfunction neuroinflammation neurovascular unit NLRP3 inflammasome Parkinson’s disease PARP1 ?-Synuclein 10.3389/fimmu.2021.794770 Frontiers in Immunology 12 794770 2022-10-12T07:53:18Z 2022-10-12T07:53:18Z 2021-12-01 Article Que, Rongfang, Zheng, Jialing, Chang, Zihan, Zhang, Wenjie, Li, Hualing, Xie, Zhenchao, Huang, Zifeng, Wang, Hai-Tao, Xu, Jiangping, Jin, Dana, Yang, Wanlin, Tan, Eng-King, Wang, Qing (2021-12-01). Dl-3-n-Butylphthalide Rescues Dopaminergic Neurons in Parkinson’s Disease Models by Inhibiting the NLRP3 Inflammasome and Ameliorating Mitochondrial Impairment. Frontiers in Immunology 12 : 794770. ScholarBank@NUS Repository. https://doi.org/10.3389/fimmu.2021.794770 1664-3224 https://scholarbank.nus.edu.sg/handle/10635/232274 Attribution 4.0 International https://creativecommons.org/licenses/by/4.0/ Frontiers Media S.A. Scopus OA2021
institution National University of Singapore
building NUS Library
continent Asia
country Singapore
Singapore
content_provider NUS Library
collection ScholarBank@NUS
topic dl-3-n-Butylphthalide
mitochondrial dysfunction
neuroinflammation
neurovascular unit
NLRP3 inflammasome
Parkinson’s disease
PARP1
?-Synuclein
spellingShingle dl-3-n-Butylphthalide
mitochondrial dysfunction
neuroinflammation
neurovascular unit
NLRP3 inflammasome
Parkinson’s disease
PARP1
?-Synuclein
Que, Rongfang
Zheng, Jialing
Chang, Zihan
Zhang, Wenjie
Li, Hualing
Xie, Zhenchao
Huang, Zifeng
Wang, Hai-Tao
Xu, Jiangping
Jin, Dana
Yang, Wanlin
Tan, Eng-King
Wang, Qing
Dl-3-n-Butylphthalide Rescues Dopaminergic Neurons in Parkinson’s Disease Models by Inhibiting the NLRP3 Inflammasome and Ameliorating Mitochondrial Impairment
description 10.3389/fimmu.2021.794770
author2 DUKE-NUS MEDICAL SCHOOL
author_facet DUKE-NUS MEDICAL SCHOOL
Que, Rongfang
Zheng, Jialing
Chang, Zihan
Zhang, Wenjie
Li, Hualing
Xie, Zhenchao
Huang, Zifeng
Wang, Hai-Tao
Xu, Jiangping
Jin, Dana
Yang, Wanlin
Tan, Eng-King
Wang, Qing
format Article
author Que, Rongfang
Zheng, Jialing
Chang, Zihan
Zhang, Wenjie
Li, Hualing
Xie, Zhenchao
Huang, Zifeng
Wang, Hai-Tao
Xu, Jiangping
Jin, Dana
Yang, Wanlin
Tan, Eng-King
Wang, Qing
author_sort Que, Rongfang
title Dl-3-n-Butylphthalide Rescues Dopaminergic Neurons in Parkinson’s Disease Models by Inhibiting the NLRP3 Inflammasome and Ameliorating Mitochondrial Impairment
title_short Dl-3-n-Butylphthalide Rescues Dopaminergic Neurons in Parkinson’s Disease Models by Inhibiting the NLRP3 Inflammasome and Ameliorating Mitochondrial Impairment
title_full Dl-3-n-Butylphthalide Rescues Dopaminergic Neurons in Parkinson’s Disease Models by Inhibiting the NLRP3 Inflammasome and Ameliorating Mitochondrial Impairment
title_fullStr Dl-3-n-Butylphthalide Rescues Dopaminergic Neurons in Parkinson’s Disease Models by Inhibiting the NLRP3 Inflammasome and Ameliorating Mitochondrial Impairment
title_full_unstemmed Dl-3-n-Butylphthalide Rescues Dopaminergic Neurons in Parkinson’s Disease Models by Inhibiting the NLRP3 Inflammasome and Ameliorating Mitochondrial Impairment
title_sort dl-3-n-butylphthalide rescues dopaminergic neurons in parkinson’s disease models by inhibiting the nlrp3 inflammasome and ameliorating mitochondrial impairment
publisher Frontiers Media S.A.
publishDate 2022
url https://scholarbank.nus.edu.sg/handle/10635/232274
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