Pluripotent stem cell-derived models of neurological diseases reveal early transcriptional heterogeneity

10.1186/s13059-021-02301-6

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Main Authors:	Sorek, Matan, Oweis, Walaa, Nissim-Rafinia, Malka, Maman, Moria, Simon, Shahar, Hession, Cynthia C., Adiconis, Xian, Simmons, Sean K., Sanjana, Neville E., Shi, Xi, Lu, Congyi, Pan, Jen Q., Xu, Xiaohong, Pouladi, Mahmoud A., Ellerby, Lisa M., Zhang, Feng, Levin, Joshua Z., Meshorer, Eran
Other Authors:	PHYSIOLOGY
Format:	Article
Published:	BioMed Central Ltd 2022
Subjects:	Huntington’s disease Neurodegenerative diseases Neurological diseases Pluripotent stem cells scRNA-seq Single cell Smart-seq2 Stem cell model Transcriptional heterogeneity
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/232345
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Institution:	National University of Singapore

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spelling	sg-nus-scholar.10635-2323452022-10-12T07:58:04Z Pluripotent stem cell-derived models of neurological diseases reveal early transcriptional heterogeneity Sorek, Matan Oweis, Walaa Nissim-Rafinia, Malka Maman, Moria Simon, Shahar Hession, Cynthia C. Adiconis, Xian Simmons, Sean K. Sanjana, Neville E. Shi, Xi Lu, Congyi Pan, Jen Q. Xu, Xiaohong Pouladi, Mahmoud A. Ellerby, Lisa M. Zhang, Feng Levin, Joshua Z. Meshorer, Eran PHYSIOLOGY Huntington’s disease Neurodegenerative diseases Neurological diseases Pluripotent stem cells scRNA-seq Single cell Smart-seq2 Stem cell model Transcriptional heterogeneity 10.1186/s13059-021-02301-6 Genome Biology 22 1 73 2022-10-12T07:58:03Z 2022-10-12T07:58:03Z 2021-03-04 Article Sorek, Matan, Oweis, Walaa, Nissim-Rafinia, Malka, Maman, Moria, Simon, Shahar, Hession, Cynthia C., Adiconis, Xian, Simmons, Sean K., Sanjana, Neville E., Shi, Xi, Lu, Congyi, Pan, Jen Q., Xu, Xiaohong, Pouladi, Mahmoud A., Ellerby, Lisa M., Zhang, Feng, Levin, Joshua Z., Meshorer, Eran (2021-03-04). Pluripotent stem cell-derived models of neurological diseases reveal early transcriptional heterogeneity. Genome Biology 22 (1) : 73. ScholarBank@NUS Repository. https://doi.org/10.1186/s13059-021-02301-6 1474-7596 https://scholarbank.nus.edu.sg/handle/10635/232345 Attribution 4.0 International https://creativecommons.org/licenses/by/4.0/ BioMed Central Ltd Scopus OA2021
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	Huntington’s disease Neurodegenerative diseases Neurological diseases Pluripotent stem cells scRNA-seq Single cell Smart-seq2 Stem cell model Transcriptional heterogeneity
spellingShingle	Huntington’s disease Neurodegenerative diseases Neurological diseases Pluripotent stem cells scRNA-seq Single cell Smart-seq2 Stem cell model Transcriptional heterogeneity Sorek, Matan Oweis, Walaa Nissim-Rafinia, Malka Maman, Moria Simon, Shahar Hession, Cynthia C. Adiconis, Xian Simmons, Sean K. Sanjana, Neville E. Shi, Xi Lu, Congyi Pan, Jen Q. Xu, Xiaohong Pouladi, Mahmoud A. Ellerby, Lisa M. Zhang, Feng Levin, Joshua Z. Meshorer, Eran Pluripotent stem cell-derived models of neurological diseases reveal early transcriptional heterogeneity
description	10.1186/s13059-021-02301-6
author2	PHYSIOLOGY
author_facet	PHYSIOLOGY Sorek, Matan Oweis, Walaa Nissim-Rafinia, Malka Maman, Moria Simon, Shahar Hession, Cynthia C. Adiconis, Xian Simmons, Sean K. Sanjana, Neville E. Shi, Xi Lu, Congyi Pan, Jen Q. Xu, Xiaohong Pouladi, Mahmoud A. Ellerby, Lisa M. Zhang, Feng Levin, Joshua Z. Meshorer, Eran
format	Article
author	Sorek, Matan Oweis, Walaa Nissim-Rafinia, Malka Maman, Moria Simon, Shahar Hession, Cynthia C. Adiconis, Xian Simmons, Sean K. Sanjana, Neville E. Shi, Xi Lu, Congyi Pan, Jen Q. Xu, Xiaohong Pouladi, Mahmoud A. Ellerby, Lisa M. Zhang, Feng Levin, Joshua Z. Meshorer, Eran
author_sort	Sorek, Matan
title	Pluripotent stem cell-derived models of neurological diseases reveal early transcriptional heterogeneity
title_short	Pluripotent stem cell-derived models of neurological diseases reveal early transcriptional heterogeneity
title_full	Pluripotent stem cell-derived models of neurological diseases reveal early transcriptional heterogeneity
title_fullStr	Pluripotent stem cell-derived models of neurological diseases reveal early transcriptional heterogeneity
title_full_unstemmed	Pluripotent stem cell-derived models of neurological diseases reveal early transcriptional heterogeneity
title_sort	pluripotent stem cell-derived models of neurological diseases reveal early transcriptional heterogeneity
publisher	BioMed Central Ltd
publishDate	2022
url	https://scholarbank.nus.edu.sg/handle/10635/232345
_version_	1749178863949185024

Pluripotent stem cell-derived models of neurological diseases reveal early transcriptional heterogeneity

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