Haploinsufficiency of CYP8B1 associates with increased insulin sensitivity in humans

• Main Authors: Zhong, S, Chèvre, R, Castaño Mayan, D, Corlianò, M, Cochran, BJ, Sem, KP, van Dijk, TH, Peng, J, Tan, LJ, Hartimath, SV, Ramasamy, B, Cheng, P, Groen, AK, Kuipers, F, Goggi, JL, Drum, C, van Dam, RM, Tan, RS, Rye, KA, Hayden, MR, Cheng, CY, Chacko, S, Flannick, J, Sim, X, Tan, HC, Singaraja, RR
• Other Authors: DUKE-NUS MEDICAL SCHOOL
• Format: Article
• Published: American Society for Clinical Investigation 2022
• Subjects: Endocrinology; Insulin signaling; Humans; Steroid 12-alpha-Hydroxylase; Insulin Resistance; Insulin; Haploinsufficiency; Bile Acids and Salts; Cholic Acid; Glucose
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/234689
• Institution: National University of Singapore

10.1172/JCI152961