The H. pylori CagA Oncoprotein Induces DNA Double Strand Breaks through Fanconi Anemia Pathway Downregulation and Replication Fork Collapse

• Main Authors: Kolinjivadi, Arun Mouli, Sankar, Haresh, Choudhary, Ramveer, Tay, Lavina Sierra, Tan, Tuan Zea, Murata-Kamiya, Naoko, Voon, Dominic Chih-Cheng, Kappei, Dennis, Hatakeyama, Masanori, Krishnan, Vaidehi, Ito, Yoshiaki
• Other Authors: CANCER SCIENCE INSTITUTE OF SINGAPORE
• Format: Article
• Language: English
• Published: MDPI 2023
• Subjects: Science & Technology; Life Sciences & Biomedicine; Physical Sciences; Biochemistry & Molecular Biology; Chemistry, Multidisciplinary; Chemistry; pylori; DNA replication; CagA; DNA double strand breaks; Fanconi Anemia; gamma H2AX; HELICOBACTER-PYLORI; GASTRIC-CANCER; GENOME INSTABILITY; INFECTION; BRCA2; DEGRADATION; ERADICATION; PROTEIN; FANCD2; RISK
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/239102
• Institution: National University of Singapore

10.3390/ijms23031661